M
Manju Saraswathy
Researcher at Wisconsin Institutes for Discovery
Publications - 10
Citations - 462
Manju Saraswathy is an academic researcher from Wisconsin Institutes for Discovery. The author has contributed to research in topics: Nanogel & Nanocarriers. The author has an hindex of 5, co-authored 8 publications receiving 386 citations. Previous affiliations of Manju Saraswathy include South Dakota State University & University of Colorado Denver.
Papers
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Journal ArticleDOI
Different strategies to overcome multidrug resistance in cancer.
Manju Saraswathy,Shaoqin Gong +1 more
TL;DR: This review covers the various multidrug resistance mechanisms observed in cancer cells as well as the various strategies developed to overcome these MDR mechanisms.
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Recent developments in the co-delivery of siRNA and small molecule anticancer drugs for cancer treatment
Manju Saraswathy,Shaoqin Gong +1 more
TL;DR: The synergistic effects of combinatorial anticancer drug and siRNA therapy in various cancer models employing multifunctional drug/siRNA co-delivery nanocarriers have been discussed.
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Topical gene silencing by iontophoretic delivery of an antisense oligonucleotide–dendrimer nanocomplex: the proof of concept in a skin cancer mouse model
Venkata Vamsi Krishna Venuganti,Manju Saraswathy,Chandradhar Dwivedi,Radhey S. Kaushik,Omathanu Perumal +4 more
TL;DR: The findings from this study demonstrate that dendrimers are promising nanocarriers for developing topical gene silencing approaches for skin diseases.
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Multifunctional drug nanocarriers formed by cRGD-conjugated βCD-PAMAM-PEG for targeted cancer therapy.
TL;DR: NPs formed by βCD-PAMAM-PEG-cRGD with a high drug payload may significantly improve the anticancer efficacy by tumor-targeted delivery and enhanced cellular uptake.
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Thiol-functionalized nanogels as reactive plasticizers for crosslinked polymer networks
TL;DR: The results indicate that the application of thiol-functionalized nanogel as plasticizers to alter the bulk properties of the parent matrix while mitigating plasticizer migration by covalently crosslinking the nanogels within the polymer matrix provides a simple yet efficient technique to generate network-specific plasticizers with the ability to alter targeted properties within polymers.