M
Manoj K. Gottipati
Researcher at Ohio State University
Publications - 27
Citations - 390
Manoj K. Gottipati is an academic researcher from Ohio State University. The author has contributed to research in topics: Glial fibrillary acidic protein & Astrocyte. The author has an hindex of 9, co-authored 26 publications receiving 311 citations. Previous affiliations of Manoj K. Gottipati include Rensselaer Polytechnic Institute & University of Alabama at Birmingham.
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Journal ArticleDOI
Enhanced Ca2+-dependent glutamate release from astrocytes of the BACHD Huntington’s disease mouse model
William Lee,Reno C. Reyes,Manoj K. Gottipati,Karon Lewis,Mathieu Lesort,Vladimir Parpura,Vladimir Parpura,Michelle Gray +7 more
TL;DR: This work identifies a new mechanism in astrocytes that could lead to increased levels of extracellular glutamate in HD and thus may contribute to excitotoxicity in this devastating disease.
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Imaging of mitochondrial Ca2+ dynamics in astrocytes using cell-specific mitochondria-targeted GCaMP5G/6s: Mitochondrial Ca2+ uptake and cytosolic Ca2+ availability via the endoplasmic reticulum store
TL;DR: A novel approach to image mitochondrial Ca( 2+) dynamics as well as Ca(2+) interplay between the endoplasmic reticulum and mitochondria, which is relevant for neuronal and astrocytic functions in health and disease is provided.
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Chemically functionalized water-soluble single-walled carbon nanotubes modulate morpho-functional characteristics of astrocytes
Manoj K. Gottipati,Irina Kalinina,Elena Bekyarova,Robert C. Haddon,Robert C. Haddon,Vladimir Parpura,Vladimir Parpura,Vladimir Parpura +7 more
TL;DR: By affecting astrocytes, ws-SWCNTs could provide for a more comprehensive re-establishment of the brain computational power, and could have more beneficial effects at the injury site than previously thought.
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Biomaterial Approaches to Modulate Reactive Astroglial Response.
TL;DR: It is suggested that in order to improve biomaterial designs for spinal cord injury applications, investigators should more thoroughly consider the astrocyte response to such designs.
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Chemically Functionalized Single-Walled Carbon Nanotube Films Modulate the Morpho-Functional and Proliferative Characteristics of Astrocytes
Manoj K. Gottipati,Josheua J. Samuelson,Irina Kalinina,Elena Bekyarova,Robert C. Haddon,Robert C. Haddon,Vladimir Parpura,Vladimir Parpura +7 more
TL;DR: CNT films, as a coating material for electrodes used in brain machine interface, could reduce astrogliosis around the site of implantation.