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Manuel Puig-Domingo

Researcher at University of Texas Health Science Center at San Antonio

Publications -  10
Citations -  203

Manuel Puig-Domingo is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Melatonin & Hamster. The author has an hindex of 9, co-authored 10 publications receiving 202 citations. Previous affiliations of Manuel Puig-Domingo include University of Texas at San Antonio.

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Journal ArticleDOI

Thyroxine 5′-Deiodinase Activity in Pineal Gland and Frontal Cortex: Nighttime Increase and the Effect of Either Continuous Light Exposure or Superior Cervical Ganglionectomy*

TL;DR: The data demonstrate the existence of a 24-h rhythm of type II T4 5'-D activity in pineal gland and cortex, with peak levels occurring at night; in Pineal, the sympathetic neural input is indispensable for the rhythm, since SCGX prevented it, and in cortex, the apparent paradoxical effect of LL and SCG X on 5'D activity indicates that other mechanisms are involved in its regulation.
Journal ArticleDOI

Sexual dimorphism in N-acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin content in the Harderian gland of Syrian hamsters: changes following gonadectomy

TL;DR: Intact male hamsters had very low levels of Harderian HIOMT activity and melatonin content in comparison with the glands of the females, and testosterone implants in the castrated males led to a recovery of the original male NAT levels.
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Inhibition of pineal type-II 5'-deiodinase does not affect the nocturnal increase of N-acetyltransferase activity and melatonin content in either euthyroid or thyroidectomized rats.

TL;DR: The presence of type‐II thyroxine 5′‐deiodinase (5′‐D) activity in rat pineal gland and N‐acetyltransferase (NAT) activity, and melatonin content were measured in the same rat Pineal.
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Harderian Gland n-acetyltransferase activity in the male syrian hamster: Effects of gonadectomy, short photoperiod exposure, or subcutaneous melatonin implants

TL;DR: Castrated hamsters exposed to long days showed higher NAT activity than that of castrated animals exposed to short photoperiods indicating that light may have some influence on Harderian NAT independent of the gonadal status, and HIOMT activity and melatonin content in all these groups of male Syrian hamsters were very low.