M
Manuel Ruiz Borrego
Researcher at Services Hospital
Publications - 53
Citations - 793
Manuel Ruiz Borrego is an academic researcher from Services Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 11, co-authored 30 publications receiving 566 citations.
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Journal ArticleDOI
Adjuvant Docetaxel for High-Risk, Node-Negative Breast Cancer
Miguel Martin,Miguel Ángel Seguí,Antonio Antón,Amparo Ruiz,Manuel Ramos,Encarna Adrover,Ignacio Aranda,Álvaro Rodríguez-Lescure,Regina Große,Lourdes Calvo,Agustí Barnadas,Dolores Isla,Purificación Martínez del Prado,Manuel Ruiz Borrego,J. Zaluski,A. Arcusa,Montserrat Muñoz,José M. López Vega,J. R. Mel,Blanca Munárriz,Cristina Llorca,Carlos Jara,Emilio Alba,J. Florián,Junfang Li,José Antonio López García-Asenjo,Amparo Sáez,María José Rios,Sergio Almenar,Gloria Peiró,Ana Lluch +30 more
TL;DR: Adjuvant TAC improved the rate of disease-free survival among women with high-risk, node-negative breast cancer and was consistent, regardless of hormone-receptor status, menopausal status, or number of high- risk factors.
Proceedings ArticleDOI
Abstract GS3-00: First results from a phase III randomized clinical trial of standard adjuvant endocrine therapy (ET) +/- chemotherapy (CT) in patients (pts) with 1-3 positive nodes, hormone receptor-positive (HR+) and HER2-negative (HER2-) breast cancer (BC) with recurrence score (RS) < 25: SWOG S1007 (RxPonder)
Kevin Kalinsky,William E. Barlow,Funda Meric-Bernstam,Julie R. Gralow,Kathy S. Albain,Daniel F. Hayes,Nancy Lin,Edith A. Perez,Lori J. Goldstein,Stephen Chia,Subkhbinder Dhesy-Thind,Priya Rastogi,Emilio Alba,Suzette Delaloge,Miguel Martín,Miguel Gil,Claudia Arce-Salinas,Etienne Brain,In Hae Park,Jean-Yves Pierga,Ana Lluch,Manuel Ramos Vasquez,Manuel Ruiz Borrego,Kyung Hae Jung,Jean-Marc Ferrero,Anne F. Schott,S Shak,Priyanka Sharma,Danika L. Lew,Jieling Miao,Debu Tripathy,Gabriel N. Hortobagyi,Lajos Pusztai +32 more
TL;DR: Kalinsky et al. as mentioned in this paper showed that the potential prognostic and predictive role of recurrence score (RS) for CT benefit in postmenopausal patients with HR+, HER2-, axillary lymph node (LN)-negative BC.
Journal ArticleDOI
New Insights into the Role of the Immune Microenvironment in Breast Carcinoma
Luis de la Cruz-Merino,Antonio Barco-Sánchez,Fernando Henao Carrasco,Esteban Nogales Fernández,Ana Vallejo Benítez,Javier Brugal Molina,Antonio Martínez Peinado,Ana Grueso López,Manuel Ruiz Borrego,Manuel Codes Manuel de Villena,Víctor Sánchez-Margalet,Adoracion Nieto-Garcia,Emilio Alba Conejo,Noelia Casares Lagar,José Ibáñez Martínez +14 more
TL;DR: This review tries to summarize and elucidate new concepts and knowledge related to laboratory immune findings from a translational perspective focusing on breast cancer, paying special attention to those aspects that might have more significance in clinical practice and could be useful to design successful therapeutic strategies in the future.
Journal ArticleDOI
Epirubicin Plus Cyclophosphamide Followed by Docetaxel Versus Epirubicin Plus Docetaxel Followed by Capecitabine As Adjuvant Therapy for Node-Positive Early Breast Cancer: Results From the GEICAM/2003-10 Study
Miguel Martin,Amparo Ruiz Simón,Manuel Ruiz Borrego,Nuria Ribelles,Álvaro Rodríguez-Lescure,Montserrat Munoz-Mateu,Sonia González,Mireia Margeli Vila,Agustí Barnadas,Manuel Ramos,Sonia Del Barco Berron,Carlos Poblete Jara,Lourdes Calvo,Noelia Martínez-Jañez,Cesar Mendiola Fernandez,César A. Rodríguez,Eduardo Martínez de Dueñas,Raquel Andrés,Arrate Plazaola,Juan de la Haba-Rodriguez,J. M. López-Vega,Encarna Adrover,Ana Isabel Ballesteros,Ana Santaballa,Pedro Sánchez-Rovira,José Manuel Baena-Cañada,Maribel Casas,MC Cámara,Eva Carrasco,Ana Lluch +29 more
TL;DR: Invasive disease-free survival was significantly superior for patients with node-positive early BC who received the adjuvant standard schedule EC-T than for those who receivedThe experimental ET-X regimen, and toxicity profiles differed substantially across arms.
Journal ArticleDOI
Fluorouracil, Doxorubicin, and Cyclophosphamide (FAC) Versus FAC Followed by Weekly Paclitaxel As Adjuvant Therapy for High-Risk, Node-Negative Breast Cancer: Results From the GEICAM/2003-02 Study
Miguel Martin,Amparo Ruiz,Manuel Ruiz Borrego,Agustí Barnadas,Sonia González,Lourdes Calvo,Mireia Margeli Vila,Antonio Antón,Álvaro Rodríguez-Lescure,Miguel Angel Seguí-Palmer,Montserrat Munoz-Mateu,Joan Dorca Ribugent,J. M. López-Vega,Carlos Jara,Enrique Espinosa,Cesar Mendiola Fernandez,Raquel Andrés,Nuria Ribelles,Arrate Plazaola,Pedro Sánchez-Rovira,Javier Salvador Bofill,C. Crespo,Francisco Carabantes,Sonia Servitja,Jose Ignacio Chacon,César A. Rodríguez,Blanca Hernando,Isabel Alvarez,Eva Carrasco,Ana Lluch +29 more
TL;DR: For patients with high-risk node-negative BC, the adjuvant FAC-wP regimen was associated with a small but significant improvement in DFS compared with FAC therapy, in addition to manageable toxicity, especially regarding long-term cardiac effects.