Marc I. Chimowitz

TL;DR: In this paper, the authors provided evidence-based recommendations for the prevention of future stroke among survivors of ischemic stroke or transient ischemi-chemic attack, including the control of risk factors, intervention for vascular obstruction, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke.

TL;DR: Warfarin was associated with significantly higher rates of adverse events and provided no benefit over aspirin in this trial, and aspirin should be used in preference to warfarin for patients with intracranial arterial stenosis.

TL;DR: In patients with intracranial arterial stenosis, aggressive medical management was superior to PTAS with the use of the Wingspan stent system, both because the risk of early stroke after PTAS was high and because therisk of stroke with aggressive medical therapy alone was lower than expected.

TL;DR: This method shows good interobserver and intraobserver agreements for the measurement of intracranial stenosis of a major artery and may serve as a standard for this measurement.

TL;DR: Among patients with symptomatic intracranial stenosis, the risk of subsequent stroke in the territory of the stenotic artery is greatest with stenosis ≥70%, after recent symptoms, and in women.