M
Marc le Maire
Researcher at University of Paris-Sud
Publications - 101
Citations - 5408
Marc le Maire is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: ATPase & Endoplasmic reticulum. The author has an hindex of 39, co-authored 101 publications receiving 5223 citations. Previous affiliations of Marc le Maire include University of Nice Sophia Antipolis & Centre national de la recherche scientifique.
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Journal ArticleDOI
Interaction of membrane proteins and lipids with solubilizing detergents.
TL;DR: The nature of detergent binding by the membrane from a noncooperative to a cooperative interaction already below the critical micellar concentration is considered and it is concluded that in general binding as a monolayer ring, rather than as a micelle, is the most probable mechanism.
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The mechanism of detergent solubilization of liposomes and protein-containing membranes
TL;DR: The data suggest that detergent solubilization proceeds by a combination of a transbilayer attack, following flip-flop of detergent molecules across the lipid bilayer, and extraction of membrane components directly by detergent micelles.
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Monomeric G-Protein-Coupled Receptor as a Functional Unit
Marc Chabre,Marc le Maire +1 more
TL;DR: A molecular model is proposed for the functional coupling of a rhodopsin monomeric unit with a G-protein heterotrimer and should be valid even for GPCRs that exist as structural dimers.
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Morphological changes of phosphatidylcholine bilayers induced by melittin: vesicularization, fusion, discoidal particles
Jean Dufourcq,Jean-François Faucon,Georges Fourche,Jean-Louis Dasseux,Marc le Maire,Thaddée Gulik-Krzywicki +5 more
TL;DR: It is concluded that melittin induces a reorganization of lipid assemblies which can involve different processes, depending on experimental conditions: vesicularization of multibilayers; fusion of small lipid vesicles; fragmentation into discs and micelles.
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The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization.
Anne Op De Beeck,Roland Montserret,Sandrine Duvet,Laurence Cocquerel,René Cacan,Benoît Barberot,Marc le Maire,François Penin,Jean Dubuisson +8 more
TL;DR: Alanine scanning results and the three-dimensional molecular model obtained provide the first framework for a molecular level understanding of the mechanism of hepatitis C virus envelope glycoprotein heterodimerization.