M
Marc Morissette
Researcher at Laval University
Publications - 121
Citations - 6079
Marc Morissette is an academic researcher from Laval University. The author has contributed to research in topics: MPTP & Dopamine. The author has an hindex of 45, co-authored 114 publications receiving 5670 citations.
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Journal ArticleDOI
Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice.
Sophie Callier,Sophie Callier,Marc Morissette,Michelle Grandbois,Didier Pélaprat,Thérèse Di Paolo +5 more
TL;DR: A stereospecific neuroprotection by 17β‐estradiol of MPTP neurotoxicity is observed, which is also observed with progesterone or raloxifene treatment.
Journal ArticleDOI
Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice
Julie Blanchet,Fanny Longpré,Geneviève Bureau,Marc Morissette,Thérèse DiPaolo,Gilles Bronchti,Maria-Grazia Martinoli,Maria-Grazia Martinoli +7 more
TL;DR: Data revealed that resveratrol can counteract the toxic effects of the neurotoxin MPTP and, as such, it may be regarded as a powerful molecule for complementary neuroprotective therapy.
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Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain.
Marc Morissette,M. Le Saux,Myreille D’Astous,S. Jourdain,S. Al Sweidi,Nicolas Morin,Erika Estrada-Camarena,Pablo Mendez,Luis M. Garcia-Segura,T. Di Paolo +9 more
TL;DR: Results suggest therapeutic potential for the brain of ER specific agonists in ovariectomized rats and suggest a role for ERalpha in striatal dopamine neuroprotection.
Journal ArticleDOI
Sex and estrous cycle variations of rat striatal dopamine uptake sites.
Marc Morissette,T. Di Paolo +1 more
TL;DR: Striatal dopamine uptake site density was lower in male compared to intact female rats and was shown to fluctuate during the female estrous cycle, suggesting that gonadal hormones could influence the activity of psychoactive drugs acting on neuronal dopamine uptake sites.
Journal ArticleDOI
Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors.
TL;DR: Regional agonist estrogenic activity on brain AMPA and NMDA receptors of tamoxifen and raloxifene, like that of estradiol, is observed, whereas progesterone has limited effects or opposes the est radiol effect.