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Marc Rott

Researcher at University of Wisconsin–La Crosse

Publications -  11
Citations -  186

Marc Rott is an academic researcher from University of Wisconsin–La Crosse. The author has contributed to research in topics: Antibacterial agent & Lanostane. The author has an hindex of 7, co-authored 11 publications receiving 171 citations.

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Antibacterial Compounds from Mushrooms II: Lanostane Triterpenoids and an Ergostane Steroid with Activity Against Bacillus cereus Isolated from Fomitopsis pinicola

TL;DR: Anti- Bacillus cereus bioassay-guided fractionation of a crude extract of the American mushroom, Fomitopsis pinicola, was performed using thin-layer Chromatography, Sephadex LH-20 column chromatography, and preparative-scale HPLC to test for antibacterial activity against B. cereus.
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Antibacterial Compounds from Mushrooms I: A Lanostane-Type Triterpene and Prenylphenol Derivatives from Jahnoporus hirtus and Albatrellus flettii and Their Activities Against Bacillus cereus and Enterococcus faecalis

TL;DR: One novel compound and three others were shown to possess antimicrobial activities against these gram-positive bacteria employed as surrogates for more virulent and dangerous pathogens.
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New classes of Gram-positive selective antibacterials: inhibitors of MRSA and surrogates of the causative agents of anthrax and tuberculosis.

TL;DR: Preliminary structure–activity relationship studies indicated that both new classes of synthetic analogs, as well as the stilbenes, show promising activity against Gram-positive bacteria when at least one phenolic moiety is present, but not when absent.
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A new class of potential anti-tuberculosis agents: Synthesis and preliminary evaluation of novel acrylic acid ethyl ester derivatives.

TL;DR: Minimum inhibitory concentration assays indicated that two of these compounds have greater in vitro activity against Mycobacterium smegmatis than rifampin, one of the current, first-line anti-mycobacterial chemotherapeutic agents.
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Antibacterial Spirobisnaphthalenes from the North American Cup Fungus Urnula craterium

TL;DR: Urnucratin A (1) was found to be active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and Streptococcus pyogenes with MIC values of 2, 1, and 0.5 μg/mL, respectively.