M
Marcelo Capra
Researcher at Universidade Federal do Rio Grande do Sul
Publications - 22
Citations - 452
Marcelo Capra is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Population & Therapeutic drug monitoring. The author has an hindex of 11, co-authored 22 publications receiving 226 citations.
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Journal ArticleDOI
ETV6/RUNX1 fusion lacking prognostic effect in pediatric patients with acute lymphoblastic leukemia
Paulo Ricardo Gazzola Zen,Marcelo Capra,Lucia Mariano da Rocha Silla,Jiseh F. Loss,Mário S. Fernandes,Sidia Maria Callegari Jacques,Giorgio Adriano Paskulin +6 more
TL;DR: In this small sample population, the presence of the ETV6/RUNX1 fusion did not identify statistical difference in prognosis, and the patients had a cure rate similar to that described in literature.
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Population Pharmacokinetic and Exposure-Response Analyses for Daratumumab in Combination Therapies for Patients with Multiple Myeloma Who Have Received 1 or More Prior Lines of Therapy
X. Steven Xu,Sam Liao,Meletios A. Dimopoulos,Pieter Sonneveld,P. Joy Ho,Andrew Belch,Merav Leiba,Marcelo Capra,David Gomez,Eva Medvedova,Shinsuke Iida,Chang-Ki Min,Ming Qi,Jordan M. Schecter,Nushmia Z. Khokhar,Xiaoyu Yan,Liping Zhang,Pamela L. Clemens +17 more
TL;DR: The exposure-efficacy analyses on the data from combination therapies suggest that maximum clinical benefit to PFS, DOR, and ORR was attained for the majority of the patients with an acceptable safety profile at the recommended dose of 16 mg/kg.
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The Impact of Early Molecular Response in Event Free Survival in Patients with Chronic Myeloid Leukemia Treated with Imatinib
Laura Fogliatto,Marcelo Capra,Mariza Shaan,Tito Vanelli Costa,Mayde Seadi Torriani,Luis Carlos Zanandrea Contin,Raquel Breunig,Katia Fassina,Mario Sérgio Fernandes,Denise Almeida,Marco Antônio Schilling,Tânia Hellwig,Tiago Daltoe,Adriana Zardo,Mariangela Moschen,Moema Nene,Juarez Fontoura Silveira,Tahiane de Brum Soares,Liane Esteves Daudt,Joao Ricardo Friedrisch,Lucia Mariano da Rocha Silla +20 more
TL;DR: A significant proportion of pts achieve ERM after 3, 6 and 12 mo of imatinib therapy with better 3-year event free survival (EFS), which may could identify those pts more likely to have a favorable outcome.
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Determinação de bussulfano em plasma através de cromatografia líquida de alta eficiência com detector de arranjo de diodos e derivatização com dietilditiocarbamato de sódio
Charline Fernanda Backes,Sandrine Comparsi Wagner,Fernando Dal Pont Morisso,Marina Venzon Antunes,Rafael Linden,Marcelo Capra +5 more
TL;DR: In this article, a high performance liquid chromatographic-diode array detection method for the determination of busulfan in plasma was developed and validated, which presented adequate specificity, linearity, precision and accuracy.
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Biosimilar Filgrastim for Progenitor-Cell Mobilization prior to Autologous Transplantation: Retrospective Analysis of Patients with Multiple Myeloma and Lymphomas
TL;DR: It is suggested that Filgrastine® is associated with the expected success rates in PBPC harvest for autologous transplantation, despite its observational nature.