Marcelo L. Santoro

TL;DR: The doses of antivenom recommended in Brazil and used in this study may be unnecessarily high, resulting in an unacceptably high incidence of reactions.

TL;DR: It is suggested that not only venom from adult specimens, but also from specimens at other ontogenetic stages should be included in the venom pool used for raising antibodies, because Bothrops antivenin can efficaciously neutralize proteins lacking in the adult venom pool, especially those that promote more intense hemostatic disturbances in victims of newborn snakes.

TL;DR: The results indicate that the venoms from the three studied subspecies of C. durissus were very similar, except for minor differences in paw edema-inducing activity, electrophoretic profile, phospholipase A2 activity, crotamine-like activity and inorganic element contents ofC.d.

TL;DR: Patagonfibrase may play a key role in the pathogenesis of disturbances that occur in P. patagoniensis envenomation, and may be used as a biological tool to explore many facets of hemostasis.

TL;DR: Thrombocytopenia on admission is positively associated with the development of systemic bleeding and the severity of envenoming, and may also be a useful prognostic indicator for theDevelopment of local complications, such as necrosis.