Showing papers in "Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology in 1999"
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01 Jul 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: It is suggested that independence of seasonal variation should be seen as a desirable feature of a bioindicator molecule where such molecules show seasonal variation, however, this should be incorporated into interpretation of biomonitoring studies by the use of appropriate controls.
243 citations
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01 Jan 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The comparison with IC50 values of other aquatic species, indicates a higher CA sensitivity for C. granulata to pollutants.
174 citations
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01 Jun 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The VTG ELISA could be useful for the detection of estrogenic properties associated with certain compounds and could be easily incorporated into standard laboratory toxicity assays using this species.
167 citations
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01 Mar 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The data showed that Cadmium exposure produces significant cadmium uptake in tissues, and in kidney and liver, the toxic concentration increased as the concentration of pollutant in water increased.
130 citations
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01 Feb 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: During marine animal embryogenesis the activities of lipoxygenase and most of the examined antioxidant enzymes tended to increase in eggs and especially in hatching larvae, while the contents of low molecular weight antioxidants were decreased.
117 citations
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01 Jun 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: It is concluded that seasonal changes related to food intake and reproductive cycle induce changes inPeroxisomal parameters that can be compared to typical peroxisome proliferation, with a 25-fold increase in AOX activity and an 8-fold increases in the peroxISomal numerical density in early spring.
104 citations
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01 Oct 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Advances made in the understanding of neurosteroids biosynthesis, including neuronal neurosteroidogenesis, in a variety of vertebrate types are summarized.
103 citations
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01 Mar 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Propiconazoles exposure through the water changed the properties of the brown trout hepatic CYP1A and GST, and these changes may be used as a bioindicator on the molecular level of exposure and effect of propiconazole in controlled experiments.
92 citations
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01 Mar 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Surprisingly, these cholinesterases were poorly inhibited by organophosphorous compounds compared to enzymes from other sources, which suggests that these bivalves could be used as a biomarker for acute rather than chronic contaminations by anticholineterase insecticides.
88 citations
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01 Jan 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The results indicate that the venoms from the three studied subspecies of C. durissus were very similar, except for minor differences in paw edema-inducing activity, electrophoretic profile, phospholipase A2 activity, crotamine-like activity and inorganic element contents ofC.d.
83 citations
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01 Feb 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: R. philippinarum can be considered a bioindicator species for cadmium and lead accumulation and ALT could be useful as biomarker of sublethal stress for these metals in soft tissues and gills can be consider an adequate target tissue for copper.
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01 Nov 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: A baseline for the activities of the selected enzymes in female eelpout is established, which is important for the environmental monitoring using this fish species, mainly around the Baltic Sea.
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01 Jun 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: At hepatic level, G115 increases the antioxidant capacity, with a marked reduction of the effects of the oxidative stress induced by the exhaustive exercise, showing a clear hepatoprotective effect.
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01 May 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: In this article, the effects of a calcium-dependent mannose-binding lectin isolated from the serum of Atlantic salmon on Aeromonas salmonicida viability and the anti-A. Salmonicida activity were investigated.
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01 Feb 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: This study provides evidence that toads exposed to coal combustion wastes may be less efficient at responding to additional environmental stressors and may suggest disruption of hepatic enzymes responsible for the metabolic clearance of steroid hormones.
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01 Nov 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Impairment of intestinal ion and water transport as a result of silver intake via drinking could be an important part of the fatal cascade of physiological effects observed in marine fish during acute silver exposure.
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01 Jun 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: MTLPs in males of R. decussatus could be proposed as suitable biomarker for detecting metal contamination and a non-linear model based on the Box-Cox transformation showed that these two factors affected MTLP levels, but were less important than metals.
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01 Sep 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The above data suggest that insulin, together with other factors, may act to increase the levels of IGF-I in plasma.
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01 Feb 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The high degree of untranslated region similarity between each isoform indicates that these additional forms of metallothionein present in the blue sea mussel are recent gene duplication events in the Mytilus lineage.
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01 Oct 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The major component in the muscle of Alaskan subsistence fish was methyl mercury and no correlation was observed between Hsp 60 or Hsp 70 expression in gill tissue and mercury concentrations in muscle tissue.
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01 Nov 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Ascorbic acid has a protective effect on alloxan-induced damage by maintaining the activity of cellular antioxidants and the loss of copper and zinc from testes.
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01 May 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: In this article, the effects of nickel (10-100 ppm added as NiCl2) was studied to determine its effects on reproduction of Wistar rats in nine experimental groups, females, males or both were exposed to nickel in drinking water.
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01 May 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Binding experiments using biotinylated lectin revealed that it specifically recognizes and binds to mannose on the surfaces of two salmon pathogens, Vibrio anguillarum and Aeromonas salmonicida, implying an immunological role for this lectin in Atlantic salmon.
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01 Jan 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: In vitro assays with dissolved metabolites indicated no adverse effects of beauverolide L or cyclosporin A on attachment or spreading of isolated plasmatocytes but dose-dependent inhibition of their phagocytic activity.
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01 May 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Chronic exposures to metals caused no substantial alterations in the circadian rhythm of bioluminescence glow, indicating that the biological clock of this dinoflagellate is not sensitive to these metals at the concentrations tested.
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01 Nov 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: Increases in the serum concentration of PRLs and GH, and in the pituitary content of GH in response to fasting support the notion that these hormones are involved in the regulation of the use of metabolic substrates in tilapia and suggest GH has actions in reproduction.
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01 Jan 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: It is indicated that crucian carp have the ability to produce metallothionein in response to various kinds of environmental stress and that violent air-pumping stress in crucifixian carp may induce MT synthesis, in part, via the release of endogenous factor(s), such as glucocorticoids.
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01 May 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: It is concluded that the metal-induced inhibition in hepatic 5'D-I activity is mediated through LPO, and that the antioxidant vitamin E to cadmium intoxicated chickens restored thyroid function by maintaining normal hepatic 4-D- I activity and serum thyroid hormone concentrations.
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01 Jun 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: At different periods of the year specimens of Mytilus galloprovincialis were exposed to 0.5 microg Cd/ml seawater for 7 days, Metallothionein was the main ligand responsible for Cd accumulation and this protein reached a maximum between May and June.
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01 Jan 1999-Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology
TL;DR: The decline in chitobiase activity after exposure to diethyl phthalate, 4-(tert)-octylphenol, and PCB29 along with the delayed molting they cause strongly suggests that these xenobiotics disturb the Y-organ-ecdysteroid receptor axis.