M
Marco Canepa
Researcher at University of Genoa
Publications - 153
Citations - 3049
Marco Canepa is an academic researcher from University of Genoa. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 26, co-authored 110 publications receiving 2060 citations. Previous affiliations of Marco Canepa include Johns Hopkins University & National Institutes of Health.
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Journal ArticleDOI
The association between leptin and depressive symptoms is modulated by abdominal adiposity
Yuri Milaneschi,Yuri Milaneschi,Angelina R. Sutin,Angelina R. Sutin,Antonio Terracciano,Marco Canepa,Marco Canepa,Kristofer S. Gravenstein,Josephine M. Egan,Nicole Vogelzangs,Jack M. Guralnik,Stefania Bandinelli,Brenda W.J.H. Penninx,Luigi Ferrucci +13 more
TL;DR: It is suggested that low leptin signaling rather than low leptin concentration is a risk factor for depression, and proxy measures of leptin signaling should be developed by combining information on abdominal adiposity and leptin level to be used for clinical and research applications.
Journal ArticleDOI
Diagnostic and Therapeutic Gaps in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.
Marco Canepa,Frits M.E. Franssen,Horst Olschewski,Mitja Lainscak,Michael Böhm,Luigi Tavazzi,Stephan Rosenkranz +6 more
TL;DR: This state-of-the-art review summarizes current challenges in the implementation of recommended spirometry for COPD diagnosis in patients with HF and current underuse and underdosing of BBs in patientswith HF and COPD despite guideline recommendations.
Journal ArticleDOI
The relationship between visceral adiposity and left ventricular diastolic function: Results from the Baltimore Longitudinal Study of Aging
Marco Canepa,James B. Strait,Yuri Milaneschi,Majd AlGhatrif,Ramona Ramachandran,Sokratis Makrogiannis,Monika Moni,Melissa David,Claudio Brunelli,Edward G. Lakatta,Luigi Ferrucci +10 more
TL;DR: Increased visceral adiposity is associated with LV diastolic dysfunction, possibly through a metabolic pathway involving blood lipids and ectopic fat accumulation rather than adipokines.
Journal ArticleDOI
Prevalence and Prognostic Impact of Chronic Obstructive Pulmonary Disease in Patients with Chronic Heart Failure: Data from the GISSI-HF Trial
Marco Canepa,Pier Luigi Temporelli,Andrea Rossi,Lucio Gonzini,Gian Luigi Nicolosi,Lidia Staszewsky,Roberto Marchioli,Aldo P. Maggioni,Luigi Tavazzi +8 more
TL;DR: Increased awareness and improved management of COPD may reduce the burden of this morbidity to patients with heart failure, and COPD is an independent predictor of mortality and hospitalizations in ambulatory HF patients.
Journal ArticleDOI
Comparison of clinical presentation, left ventricular morphology, hemodynamics, and exercise tolerance in obese versus nonobese patients with hypertrophic cardiomyopathy.
Marco Canepa,Marco Canepa,Marco Canepa,Lars Sorensen,Iraklis Pozios,Veronica L Dimaano,Hong Chang Luo,Hong Chang Luo,Aurelio Pinheiro,James B. Strait,Claudio Brunelli,M. Roselle Abraham,Luigi Ferrucci,Theodore P. Abraham +13 more
TL;DR: Obesity is associated with larger LV mass, worse symptoms, lower exercise tolerance, and labile obstructive hemodynamics in HC, and the association with increased outflow tract gradients has particular importance as contribution of obesity to the pressure gradients may influence clinical decisions in labiles obstructive HC.