M
Marco Trizzino
Researcher at Wistar Institute
Publications - 55
Citations - 1194
Marco Trizzino is an academic researcher from Wistar Institute. The author has contributed to research in topics: Hydraenidae & Gene. The author has an hindex of 15, co-authored 52 publications receiving 853 citations. Previous affiliations of Marco Trizzino include University of Insubria & University of Pennsylvania.
Papers
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Journal ArticleDOI
Transposable elements are the primary source of novelty in primate gene regulation.
Marco Trizzino,YoSon Park,Marcia Holsbach-Beltrame,Katherine Aracena,Katelyn Mika,Minal Çalışkan,George H. Perry,Vincent J. Lynch,Christopher D. Brown +8 more
TL;DR: The critical role of TEs in primate gene regulation is demonstrated and potential mechanisms underlying evolutionary divergence among the primate species through the noncoding genome are illustrated.
Journal ArticleDOI
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis
Alessandro Carrer,Sophie Trefely,Sophie Trefely,Steven Zhao,Sydney L. Campbell,Robert J. Norgard,Kollin Schultz,Simone Sidoli,Joshua L.D. Parris,Hayley C. Affronti,Sharanya Sivanand,Shaun Egolf,Yogev Sela,Marco Trizzino,Alessandro Gardini,Benjamin A. Garcia,Nathaniel W. Snyder,Ben Z. Stanger,Kathryn E. Wellen +18 more
TL;DR: It is found that acetyl-CoA abundance is elevated in KRAS-mutant acinar cells and that its use in the mevalonate pathway supports acinar-to-ductal metaplasia (ADM), and a key role for the metabolic enzyme ACLY is identified in pancreatic carcinogenesis.
Journal ArticleDOI
Transposable elements generate regulatory novelty in a tissue-specific fashion.
TL;DR: It is demonstrated that TEs can potentially contribute to the turnover of regulatory sequences in a tissue-specific fashion and correlates with tissue- specific variations in the expression of the nearest genes.
Journal ArticleDOI
The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II.
Marco Trizzino,Elisa Barbieri,Ana Petracovici,Shuai Wu,Sarah A. Welsh,Tori A. Owens,Silvia Licciulli,Rugang Zhang,Alessandro Gardini +8 more
TL;DR: The results provide insight into ARID1A-mediated tumorigenesis and unveil functions of SWI/SNF in modulating RNAPII dynamics.
Journal Article
Preliminary re-examination of genus-level taxonomy of the pollen beetle subfamily Meligethinae (Coleoptera: Nitidulidae)
Paolo Audisio,Andrew R. Cline,A. De Biase,Gloria Antonini,Emiliano Mancini,Marco Trizzino,L Costantini,S Strika,Francesco Lamanna,Pierfilippo Cerretti +9 more
TL;DR: Genus-level taxonomy of Meligethinae (Nitidulidae) is presented, and type species of all recognized genera are indicated and/or indicated, a preliminary check list of inclusive described species is provided.