M
Marcos Felipe Pinatto-Botelho
Researcher at University of São Paulo
Publications - 9
Citations - 97
Marcos Felipe Pinatto-Botelho is an academic researcher from University of São Paulo. The author has contributed to research in topics: Selenium & Micelle. The author has an hindex of 4, co-authored 8 publications receiving 63 citations.
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Journal ArticleDOI
Synthesis and biological properties of selenium- and tellurium-containing dyes
Javier Fernández-Lodeiro,Marcos Felipe Pinatto-Botelho,Antônio A. Soares-Paulino,Augusto Cesar Gonçalves,Bruno A. Sousa,Cleverson Princival,Alcindo A. Dos Santos +6 more
TL;DR: In this article, the synthesis and biological applications of organoseleno-and organotelluro-based molecular dyes are discussed, including the most relevant applications for photodynamic therapy (PDT), fluorescent probes for the detection of endogenous reactive oxygen species (ROS), natural bioreductors like glutathione (GSH) and metals present in physiological systems.
Journal ArticleDOI
Synthesis, biophysical and functional studies of two BP100 analogues modified by a hydrophobic chain and a cyclic peptide.
Gustavo P.B. Carretero,Greice Kelle Viegas Saraiva,Ana C.G. Cauz,Ana C.G. Cauz,Magali A. Rodrigues,Sumika Kiyota,Karin A. Riske,Alcindo A. Dos Santos,Marcos Felipe Pinatto-Botelho,Marcelo P. Bemquerer,Frederico J. Gueiros-Filho,Hernan Chaimovich,Shirley Schreier,Iolanda M. Cuccovia +13 more
TL;DR: It is concluded that at high concentrations, all three peptides act by a carpet mechanism, while at low concentrations the peptides acted by disorganizing the lipid bilayer, probably causing membrane thinning.
Journal ArticleDOI
Organic Selenium Reaches the Central Nervous System and Downmodulates Local Inflammation: A Complementary Therapy for Multiple Sclerosis?
Juliana Helena dos Santos de Toledo,Thais Fernanda de Campos Fraga-Silva,Patrícia Aparecida Borim,Larissa Ragozo Cardoso de Oliveira,Evelyn da Silva Oliveira,Larissa Lucena Périco,Clélia Akiko Hiruma-Lima,Adriana Aparecida Lopes de Souza,Carlos Alberto Ferreira de Oliveira,Pedro de Magalhães Padilha,Marcos Felipe Pinatto-Botelho,Alcindo A. Dos Santos,Alexandrina Sartori,Sofia Fernanda Gonçalves Zorzella-Pezavento +13 more
TL;DR: It is indicated that LAD-βSe, and possibly other derivatives containing Se, are able to reach the CNS and have the potential to be used as preventive and therapeutic measures in distinct clinical forms of MS.
Journal Article
Evaluation of a special combination of glucan with organic selenium derivative in different murine tumor models.
TL;DR: This study showed that a combination of yeast-derived β-glucan and a selenium-linked pseudodisaccharide strongly suppressed the growth of all three types of cancers, most likely via the interaction with natural anticancer antibodies.
Journal ArticleDOI
Experimental mapping of a pH gradient from a positively charged micellar interface to bulk solution
Caroline Dutra Lacerda,Marcos F. Calegari Andrade,Phillipe de Santana Pessoa,Fernanda M. Prado,Paulo Augusto Rodrigues Pires,Marcos Felipe Pinatto-Botelho,Felipe Wodtke,Alcindo A. Dos Santos,Luís G. Dias,Filipe S. Lima,Hernan Chaimovich,Iolanda M. Cuccovia +11 more
TL;DR: In this article, the apparent pKa (pKap) of benzoic acid derivatives with surfactant micelles was calculated by UV spectroscopy, showing that the dissociation of substituted benzoates occurred at the micellar interface in both SDS and HPS.