P
Patrícia Aparecida Borim
Researcher at Sao Paulo State University
Publications - 15
Citations - 87
Patrícia Aparecida Borim is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Atom-transfer radical-polymerization. The author has an hindex of 4, co-authored 11 publications receiving 46 citations. Previous affiliations of Patrícia Aparecida Borim include University of São Paulo.
Papers
More filters
Journal ArticleDOI
Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform
Mariana Gatto,Patrícia Aparecida Borim,Ivan Rodrigo Wolf,Taís F. Cruz,Gustavo Augusto Ferreira Mota,Aline Márcia Marques Braz,Bárbara Casella Amorim,Guilherme Targino Valente,Marjorie de Assis Golim,James Venturini,João Pessoa Araújo Júnior,Alessandra Pontillo,Alexandrina Sartori +12 more
TL;DR: The results indicate that L. infantum was unable to activate the inflammasomes during the initial interaction with THP-1 cells, and the absence of caspase-1 activation and IL-1β production after 8, 24 and 48 hours of infection.
Journal ArticleDOI
Gliotoxin Aggravates Experimental Autoimmune Encephalomyelitis by Triggering Neuroinflammation.
Thais Fernanda de Campos Fraga-Silva,Luiza Ayumi Nishiyama Mimura,Laysla de Campos Toledo Leite,Patrícia Aparecida Borim,Larissa Lumi Watanabe Ishikawa,James Venturini,Maria Sueli Parreira de Arruda,Alexandrina Sartori +7 more
TL;DR: The results indicate that GTX administered in a non-neuronal site was able to increase neuroinflammation in EAE, and CNS analyses revealed that GTX locally increased the relative expression of inflammatory genes and the cytokine production.
Journal ArticleDOI
Organic Selenium Reaches the Central Nervous System and Downmodulates Local Inflammation: A Complementary Therapy for Multiple Sclerosis?
Juliana Helena dos Santos de Toledo,Thais Fernanda de Campos Fraga-Silva,Patrícia Aparecida Borim,Larissa Ragozo Cardoso de Oliveira,Evelyn da Silva Oliveira,Larissa Lucena Périco,Clélia Akiko Hiruma-Lima,Adriana Aparecida Lopes de Souza,Carlos Alberto Ferreira de Oliveira,Pedro de Magalhães Padilha,Marcos Felipe Pinatto-Botelho,Alcindo A. Dos Santos,Alexandrina Sartori,Sofia Fernanda Gonçalves Zorzella-Pezavento +13 more
TL;DR: It is indicated that LAD-βSe, and possibly other derivatives containing Se, are able to reach the CNS and have the potential to be used as preventive and therapeutic measures in distinct clinical forms of MS.
Journal ArticleDOI
Non-carbene Complex [RuCl2(PPh3)2(azocane)] as Active Catalyst Precursor for ROMP and ATRP
Rodolpho A. N. Silva,Patrícia Aparecida Borim,Patrícia Aparecida Borim,Larissa R. Fonseca,Benedito S. Lima-Neto,José L. Silva Sá,Valdemiro P. Carvalho-Jr +6 more
TL;DR: In this article, a trigonal bipyramid geometry was synthesized, characterized (CHN elementary analysis, FTIR, EPR, and 31P NMR), and applied as catalyst precursor for ring opening metathesis polymerization and atom transfer radical polymerization (ATRP).
Journal ArticleDOI
Preclinical Therapy with Vitamin D3 in Experimental Encephalomyelitis: Efficacy and Comparison with Paricalcitol
Luiza Ayumi Nishiyama Mimura,Thais Fernanda de Campos Fraga-Silva,Larissa Ragozzo Cardoso de Oliveira,Larissa Lumi Watanabe Ishikawa,Patrícia Aparecida Borim,Carla Machado,José de Anchieta de Castro e Horta Júnior,Denise Morais da Fonseca,Alexandrina Sartori +8 more
TL;DR: In this article, the authors compared the therapeutic potential of VitD and paricalcitol (Pari), which is a non-hypercalcemic vitamin D analog, to control EAE.