Marek Malik

TL;DR: Large-scale clinical studies that utilize electrocardiography are easier to conduct using mobile technologies and the collected data are suitable for "big data" processing.

TL;DR: Rate relationship of two repolarization descriptors, namely, the so-called total cosine of the QRS-T angle (TCRT) proposed to characterize global repolarized heterogeneity, and theSo-called relative T wave residuum (TWR) linked to regional repolarizing dispersion, are investigated to suggest that both global and regional repolarsization heterogeneity are increased at faster heart rates.

TL;DR: In clinical practice, an imprecision introduced by ad hoc selected heart rate correction formula of the QT interval is unlikely to lead to erroneous conclusions if all borderline cases are carefully considered but in clinical investigations the over- or undercorrection of QTc may lead to significant and systematic bias.

TL;DR: To obtain proper insight regarding diurnal variation in QTc prolongation during pharmacologic therapy and/or to assess higher risk due to impaired autonomic regulation of ventricular repolarization, individualized heart rate correction is necessary.

TL;DR: PAF episodes are associated with faster heart rates and last longer in women, which may reflect differing autonomic responses to AF, and a slower ventricular rate during PAF in older patients probably reflects an increasing prevalence of impaired atrioventricular conduction.