M
Marek Radkowski
Researcher at Medical University of Warsaw
Publications - 149
Citations - 4687
Marek Radkowski is an academic researcher from Medical University of Warsaw. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 35, co-authored 142 publications receiving 4287 citations. Previous affiliations of Marek Radkowski include Mayo Clinic & University of Pittsburgh.
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Journal ArticleDOI
Persistence of hepatitis C virus in patients successfully treated for chronic hepatitis C.
Marek Radkowski,Juan F. Gallegos-Orozco,Joanna Jabłońska,Thomas V. Colby,Bozena Walewska-Zielecka,Joanna Kubicka,Jeffrey Wilkinson,Debra Adair,Jorge Rakela,Tomasz Laskus +9 more
TL;DR: It is suggested that in patients with SVR after therapy, small quantities of HCV RNA may persist in liver or macrophages and lymphocytes for up to 9 years, which could result in persistence of humoral and cellular immunity for many years after therapy and could present a potential risk for infection reactivation.
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Search for Hepatitis C Virus Negative-Strand RNA Sequences and Analysis of Viral Sequences in the Central Nervous System: Evidence of Replication
Marek Radkowski,Jeffrey Wilkinson,Marek Nowicki,Debra Adair,Hugo E. Vargas,Craig Ingui,Jorge Rakela,Tomasz Laskus +7 more
TL;DR: The results of the present study suggest that HCV can replicate in the central nervous system, probably in cells of the macrophage/monocyte lineage.
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Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes.
Tomasz Laskus,Marek Radkowski,Andrzej Piasek,Marek Nowicki,Andrzej Horban,Janusz Cianciara,Jorge Rakela +6 more
TL;DR: Findings imply that, in HIV-infected subjects, HCV may replicate in the same cells as HIV-1, which raises the possibility of direct interactions between these pathogens.
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Hepatitis C Virus Neuroinvasion: Identification of Infected Cells
TL;DR: It is shown that HCV infects brain microglia/macrophages and, to a lesser extent, astrocytes, and these findings could explain the biological basis of neurocognitive abnormalities in HCV infection.
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Outcome of liver transplantation in hepatitis C virus–infected patients who received hepatitis C virus–infected grafts☆☆☆
Hugo E. Vargas,Tomasz Laskus,Lianfu Wang,Randall G. Lee,Marek Radkowski,Forrest Dodson,John J. Fung,Jorge Rakela +7 more
TL;DR: HCV-infected livers transplanted into HCV- Infected recipients do not appear to convey a worse outcome in the initial years after OLT than HCVs-negative grafts, and patients in whom the donor strain became predominant after transplantation had significantly longer disease-free survival.