M
Margaret C. Wardle
Researcher at University of Illinois at Chicago
Publications - 73
Citations - 1835
Margaret C. Wardle is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Medicine & MDMA. The author has an hindex of 23, co-authored 62 publications receiving 1534 citations. Previous affiliations of Margaret C. Wardle include University of Texas at Austin & Texas Medical Center.
Papers
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Journal ArticleDOI
Amping Up Effort: Effects of d-Amphetamine on Human Effort-Based Decision-Making
Margaret C. Wardle,Michael T. Treadway,Leah M. Mayo,David H. Zald,David H. Zald,Harriet de Wit +5 more
TL;DR: This is the first demonstration in humans that dopaminergic manipulations alter willingness to exert effort for rewards, and the findings help elucidate neurochemical substrates of choice, with implications for neuropsychiatric diseases characterized by dopamine dysfunction and motivational deficits.
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Adult attachment security and college student substance use.
TL;DR: Examining the relationship between adult attachment style and use of cigarettes, alcohol, and marijuana in a sample of 212 college students highlighted the potential importance of adult attachment styles as a risk factor for drug use among college students.
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Effects of MDMA and Intranasal oxytocin on social and emotional processing.
TL;DR: The present findings provide only limited support for the idea that oxytocin produces the prosocial effects of MDMA, which increases euphoria and feelings of sociability.
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The acute effects of nicotine on positive and negative affect in adolescent smokers
Jon D. Kassel,Daniel P. Evatt,Justin E. Greenstein,Margaret C. Wardle,Marisa C. Yates,Jennifer C. Veilleux +5 more
TL;DR: The findings conform to a negative reinforcement model of nicotine effects and strongly suggest that, even among young light smokers, nicotine dependence and resultant withdrawal symptomatology may serve as motivating factors governing smoking behavior.
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Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)
Amy B. Hart,Barbara E. Engelhardt,Margaret C. Wardle,Greta Sokoloff,Matthew Stephens,Harriet de Wit,Abraham A. Palmer +6 more
TL;DR: The genetic basis of subjective responses to stimulant drugs using a GWAS approach in a modestly sized sample provides a case study for analysis of high-dimensional intermediate pharmacogenomic phenotypes, which may be more tractable than clinical diagnoses.