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Margaret J Hosie
Researcher at University of Glasgow
Publications - 175
Citations - 5789
Margaret J Hosie is an academic researcher from University of Glasgow. The author has contributed to research in topics: Feline immunodeficiency virus & Virus. The author has an hindex of 41, co-authored 164 publications receiving 5094 citations. Previous affiliations of Margaret J Hosie include The Advisory Board Company & University of Texas Medical Branch.
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Journal ArticleDOI
Shared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses.
Brian J. Willett,Laurent Picard,Margaret J Hosie,Julie D. Turner,Karen Adema,Paul R. Clapham +5 more
TL;DR: It is demonstrated that cell culture-adapted strains of FIV are able to use the alpha-chemokine receptor CXCR4 for cell fusion, suggesting a close evolutionary link between FIV and HIV and a common mechanism of infection involving an interaction between the virus and a member of the seven-transmembrane domain chemokine receptors family of molecules.
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Feline herpesvirus infection. ABCD guidelines on prevention and management
Etienne Thiry,Diane Addie,Sándor Belák,Corine Boucraut-Baralon,Herman Egberink,Tadeusz Frymus,Tim Gruffydd-Jones,Katrin Hartmann,Margaret J Hosie,Albert Lloret,Hans Lutz,Fulvio Marsilio,Maria Grazia Pennisi,Alan D Radford,Uwe Truyen,Marian C. Horzinek +15 more
TL;DR: Feline herpesvirus infections cause acute rhinitis and conjunctivitis, usually accompanied by fever, depression and anorexia, and in most cats, FHV remains latent after recovery, and they become lifelong virus carriers.
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Use of CD134 as a primary receptor by the feline immunodeficiency virus.
Masayuki Shimojima,Takayuki Miyazawa,Takayuki Miyazawa,Yasuhiro Ikeda,Elizabeth L. McMonagle,Hayley Haining,Hiroomi Akashi,Yasuhiro Takeuchi,Margaret J Hosie,Brian J. Willett +9 more
TL;DR: A primary receptor for FIV is identified as CD134 (OX40), a T cell activation antigen and costimulatory molecule that promotes viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation.
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FIV infection of the domestic cat: an animal model for AIDS
TL;DR: It is shown that the induction of protective immunity to FIV infection using inactivated virus vaccines offers hope for the development of a successful vaccine for AIDS.
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Feline infectious peritonitis. ABCD guidelines on prevention and management
Diane Addie,Sándor Belák,Corine Boucraut-Baralon,Herman Egberink,Tadeusz Frymus,Tim Gruffydd-Jones,Katrin Hartmann,Margaret J Hosie,Albert Lloret,Hans Lutz,Fulvio Marsilio,Maria Grazia Pennisi,Alan D Radford,Etienne Thiry,Uwe Truyen,Marian C. Horzinek +15 more
TL;DR: The clinical picture of FIP is highly variable, depending on the distribution of the vasculitis and pyogranulomatous lesions, and there are no controlled studies to prove any beneficial effect of corticosteroids.