M
Margaret L. Gardel
Researcher at University of Chicago
Publications - 163
Citations - 15434
Margaret L. Gardel is an academic researcher from University of Chicago. The author has contributed to research in topics: Actin cytoskeleton & Actin. The author has an hindex of 55, co-authored 146 publications receiving 13313 citations. Previous affiliations of Margaret L. Gardel include Alcatel-Lucent & University of Illinois at Chicago.
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Journal ArticleDOI
Elastic Behavior of Cross-Linked and Bundled Actin Networks
Margaret L. Gardel,Jennifer Hyunjong Shin,Fred C. MacKintosh,Lakshminarayanan Mahadevan,Paul Matsudaira,David A. Weitz +5 more
TL;DR: It is shown that networks of cross-linked and bundled actin filaments exhibit exceptional elastic behavior that reflects the mechanical properties of individual filaments, and parameterize the full range of behavior in a state diagram and elucidate its origin with a robust model.
Journal ArticleDOI
Giant dielectric constant response in a copper-titanate
Arthur P. Ramirez,Munirpallam A. Subramanian,Margaret L. Gardel,Girsh Blumberg,Der-Chiang Li,Thomas Vogt,S. M. Shapiro +6 more
TL;DR: In this paper, the authors describe a material, cubic CaCu 3 Ti 4 O 12, which exhibits a large dielectric response, the temperature-dependence of which has not been seen, to our knowledge, in any existing material.
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Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration
TL;DR: Current knowledge of the dynamic organization of the F-actin cytoskeleton in cell migration and the regulation of focal adhesion assembly and disassembly is reviewed with an emphasis on how mechanical and biochemical signaling between these two systems regulate the coordination of physical processes in cell Migration.
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Anomalous diffusion probes microstructure dynamics of entangled F-actin networks
Ian Y. Wong,Margaret L. Gardel,David R. Reichman,Eric R. Weeks,Megan T. Valentine,Andreas R. Bausch,David A. Weitz +6 more
TL;DR: Anomalous subdiffusion in colloidal tracer particles in entangled actin filament (F-actin) networks is determined to be due to the dynamics of infrequent and large jumps particles make between distinct pores in the network.
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High Resolution Traction Force Microscopy Based on Experimental and Computational Advances
TL;DR: Experimental and computational advances in improving the resolution and reliability of traction force microscopy are reported and fibroblast traction is reconstructed for the first time with a spatial resolution of approximately 1 microm.