Margaret Tartaglione

TL;DR: The AAA study will provide important information concerning the efficacy of using angiotensin-converting enzyme inhibitors to offset the effects of late anthracycline cardiotoxicity.

TL;DR: Human neuroblastoma cells lack HLA‐A,‐B,‐C molecules which can be induced in vitro by gamma interferon (γIFN), so it was hypothesized that the same induction would occur in vivo leading to tumor regression.

TL;DR: Although CHP707m is the first central nervous system PNET cell line proven to express NGF receptors, immunohistological survey of tissue sections prepared from human central nervous System PNETs showed that 13 of 35 contained NGF receptor‐positive tumor cells, suggesting more than one‐third of such tumors might be responsive to the effects of NGF.

TL;DR: A system to detect neuroblastoma (NBL) tumor cells in human bone marrow exploits the findings that NBL cells have little or no HLA antigen on the surface to define false positive cells, which can be defined because they have HLA surface antigen which Neuroblastoma cells do not express.

TL;DR: A variant of the human neuroblastoma cell line, IMR-5, was selected by a series of treatments with the monoclonal antibody PI153/3 and complement and did not differ from IMR5 in its sensitivity in lysis by other antibodies, in its lack of expression of HLA antigens, or in its capacity to form tumors in nude mice.