M
Margot Egger
Researcher at Innsbruck Medical University
Publications - 6
Citations - 440
Margot Egger is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Endothelium & Secretoneurin. The author has an hindex of 6, co-authored 6 publications receiving 412 citations. Previous affiliations of Margot Egger include Tufts University.
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Journal ArticleDOI
The Neuropeptide Catestatin Acts As a Novel Angiogenic Cytokine via a Basic Fibroblast Growth Factor–Dependent Mechanism
Markus Theurl,Wilfried Schgoer,Karin Albrecht,Johannes Jeschke,Margot Egger,Arno Beer,Danijela Vasiljevic,Song Rong,Anna Maria Wolf,Ferdinand H. Bahlmann,Josef R. Patsch,Dominik Wolf,Peter Schratzberger,Sushil K. Mahata,Rudolf Kirchmair +14 more
TL;DR: Catestatin acts as a novel angiogenic cytokine via a basic fibroblast growth factor–dependent mechanism, indicating induction of arteriogenesis and postnatal vasculogenesis.
Journal ArticleDOI
The Neuropeptide Secretoneurin Acts as a Direct Angiogenic Cytokine In Vitro and In Vivo
Rudolf Kirchmair,Roland Gander,Margot Egger,Allison Hanley,Marcy Silver,Andreas Ritsch,Toshinori Murayama,Nicole C. Kaneider,Wolfgang Sturm,Marianne Kearny,Reiner Fischer-Colbrie,Brigitte Kircher,Hannes Gaenzer,Christian J. Wiedermann,Allan H. Ropper,Douglas W. Losordo,Josef R. Patsch,Peter Schratzberger +17 more
TL;DR: Data show that secretoneurin represents a novel direct angiogenic cytokine and reiterate the coordinated relationship between nervous and vascular systems.
Journal ArticleDOI
Monocyte migration: a novel effect and signaling pathways of catestatin.
Margot Egger,Arno Beer,Markus Theurl,Wilfried Schgoer,Benjamin Hotter,Tobias Tatarczyk,Danijela Vasiljevic,Silke Frauscher,Josef Marksteiner,Josef R. Patsch,Peter Schratzberger,Angela Djanani,Sushil K. Mahata,Rudolf Kirchmair +13 more
TL;DR: It is demonstrated that catestatin dose-dependently stimulates chemotaxis of human peripheral blood monocytes, exhibiting its maximal effect at a concentration of 1 nM comparable to the established chemoattractant formylated peptide Met-Leu-Phe (fMLP).
Journal ArticleDOI
Secretoneurin, an Angiogenic Neuropeptide, Induces Postnatal Vasculogenesis
Rudolf Kirchmair,Margot Egger,Dirk H. Walter,Wolfgang Eisterer,Andreas Niederwanger,Ewald Woell,Markus Nagl,Michael T. Pedrini,Toshinori Murayama,Silke Frauscher,Allison Hanley,Marcy Silver,Marianne Brodmann,Wolfgang Sturm,Reiner Fischer-Colbrie,Douglas W. Losordo,Josef R. Patsch,Peter Schratzberger +17 more
TL;DR: The data show that the angiogenic neuropeptide secretoneurin stimulates postnatal vasculogenesis by mobilization, migration, and incorporation of endothelial progenitor cells.
Journal ArticleDOI
Hypoxia up-regulates the angiogenic cytokine secretoneurin via an HIF-1α- and basic FGF-dependent pathway in muscle cells
Margot Egger,Wilfried Schgoer,Arno Beer,Johannes Jeschke,Johannes Leierer,Markus Theurl,Silke Frauscher,Oren M. Tepper,Andreas Niederwanger,Andreas Ritsch,Marianne Kearney,Julia Wanschitz,Geoffrey C. Gurtner,Reiner Fischer-Colbrie,Guenter Weiss,Hildegunde Piza-Katzer,Douglas W. Losordo,Josef R. Patsch,Peter Schratzberger,Rudolf Kirchmair +19 more
TL;DR: Hypoxia up‐regulates the angiogenic cytokine secretoneurin via an HIF‐1α‐ and basic FGF‐dependent pathway in muscle cells by hypoxia‐inducible factor‐1 α and basic fibroblast growth factor‐dependent mechanisms.