Showing papers by "Maria Auxiliadora Coelho Kaplan published in 2003"
TL;DR: The naphthoquinone plumbagin is suggested as a promising antimicrobial agent against bacteria and yeast.
Abstract: Plumbagin is a naturally occurring naphthoquinone isolated from roots of Plumbago scandens. The plant was collected at the Campus of Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil. P. scandens is used as a traditional medicine for the treatment of several diseases. The antimicrobial activity of plumbagin was evaluated using the macrodilution method. The compound exhibited relatively specific activity against bacteria and yeast. The minimum inhibitory concentration test showed the growth inhibiton of Staphylococcus aureus at a concentration of 1.56 µg/ml and of Candida albicans at a concentration of 0.78 µg/ml. These results suggest the naphthoquinone plumbagin as a promising antimicrobial agent.
181 citations
TL;DR: These triterpenoids inhibited the growth and induced apoptosis of K562, an erythroleukemia cell line and inhibited the proliferation of Lucena 1, a vincristine-resistant derivative of K582 that displays several multidrug resistance (MDR) characteristics.
138 citations
TL;DR: A new apigeninglycoside, apigenin 6-C-Galactosyl-6"-O-beta-galactopyranoside (1), isoorientin, and a mixture of orientin and isovitexin were isolated from leaves of Cecropia lyratiloba by high-speed countercurrent chromatography using a solvent system containing ethyl acetate, butanol, methanol and water.
Abstract: A new apigeninglycoside, apigenin 6-C-galactosyl-6″-O-β-galactopyranoside (1), isoorientin, and a mixture of orientin and isovitexin were isolated from leaves of Cecropia lyratiloba by high-speed countercurrent chromatography using a solvent system containing ethyl acetate, butanol, methanol and water. The structural elucidation of 1 was based on NMR spectroscopy. Copyright © 2003 John Wiley & Sons, Ltd.
28 citations
01 Jan 2003
TL;DR: The extracts of some species of Plumbaginales and also some isolated compounds revealed to be of great importance in the search of new drugs, since they have been described in literature.
Abstract: lumbaginales belongs to the superorder Malviflorae and comprises two families, Plumbaginaceae and Limoniaceae. Its representatives are chemically characterized by the presence of naphthoquinones, flavonoids, terpenoids and steroids, many of them being the responsible for biodynamic activities. The extracts of some species of Plumbaginales and also some isolated compounds revealed to be of great importance in the search of new drugs, since they have been described in literature
15 citations
01 Dec 2003
2 citations
TL;DR: In this paper, ternary blends for application in plates chromatography were formed with styrene/butadiene/acrylinotrile (ABS), poly(vinyl chloride) (PVC), and gypsum, and were studied by solid-state carbon-13 nuclear magnetic resonance (13C NMR).
Abstract: Polymer blends were prepared to obtain a new material with specific characteristics. To prepare a miscible polymer blend, it is necessary to evaluate the chemical structure and molecular dynamics of all polymers involved and to thereby establish a structure–property relationship for these materials. In this work, ternary blends for application in plates chromatography were formed with styrene/butadiene/acrylinotrile (ABS), poly(vinyl chloride) (PVC), and gypsum, and were studied by solid-state carbon-13 nuclear magnetic resonance (13C NMR). Magic-angle spinning (MAS), cross-polarization magic-angle spinning (CPMAS), variable contact time (VCT), and proton spin-lattice relation time in the rotating frame (Tρ) were the techniques used to evaluate the miscibility, homogeneity, and compatibility of polymer blends at the molecular level. From the values of Tρ, it was verified that ABS/PVC/gypsum formed good polymer blends with some specific physical interaction at the molecular level. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 88: 293–296, 2003
1 citations