Maria B. Lai

TL;DR: It is found that TiO2 micro- and nanoparticles induced cell death on both human cell types in a concentration-related manner and it was noted that zinc oxide (ZnO) nanoparticles were the most effective,TiO2 nanoparticles the secondmost effective, and magnesium oxide (MgO), the least effective in inducing cell death in U87 cells.

TL;DR: There may be a cross-talk between signaling pathways and glycolysis in regulating Panc-1 cell survival and signaling, and a combination of agents that inhibit both energy production and cell signaling may provide a novel and effective approach to target pancreatic cancer effectively.

TL;DR: It is reported that TSPAN12 is an essential component of the NDP receptor complex and interacts with FZD4 and NDP via its extracellular loops, consistent with an action as co-receptor that enhances FzD4 ligand selectivity for NDP.

TL;DR: The results clearly demonstrate a differential regulation of signaling pathways by various isoflavones in OSCC cell lines, and tumor progression models can be utilized to study the preventive and therapeutic roles of isofavones in oral cancer cell lines.

TL;DR: The preliminary findings suggest that statin treatment may be beneficial as a therapeutic avenue for pancreatic cancer but may not have the same benefits for liver cancer.