Christopher K. Daniels

TL;DR: A comprehensive review on HSC70 from the literatures including the basic general information such as classification, structure and cellular location, genetics and function, as well as its protein association and interaction with other proteins.

TL;DR: It is found that TiO2 micro- and nanoparticles induced cell death on both human cell types in a concentration-related manner and it was noted that zinc oxide (ZnO) nanoparticles were the most effective,TiO2 nanoparticles the secondmost effective, and magnesium oxide (MgO), the least effective in inducing cell death in U87 cells.

TL;DR: Because BSO treatment accentuated Mn toxicity in both cell lines, GSH may act to combat Mn toxicity, and further investigation in oxidative stress mediated by glutathione depletion will unravel new Mn toxicity mechanism(s).

TL;DR: The hypothesis that Mn induces alterations in energy metabolism in neural cells by interfering with the activities of various glycolytic and TCA cycle enzymes is investigated using human neuroblastoma and astrocytoma cells and the results suggest the two cell types exhibited differential susceptibility toward the Mn-induced effects.

TL;DR: The results suggest that biochanin A is effective in reducing pancreatic cancer cell survival by inhibiting their proliferation and inducing apoptosis, which may lead to novel approaches to treat pancreatic cancers using isoflavones in combination with other therapeutic drugs.