M
María-Carmen López de Las Hazas
Researcher at IMDEA
Publications - 42
Citations - 1102
María-Carmen López de Las Hazas is an academic researcher from IMDEA. The author has contributed to research in topics: Hydroxytyrosol & Medicine. The author has an hindex of 14, co-authored 31 publications receiving 567 citations. Previous affiliations of María-Carmen López de Las Hazas include University of Lleida & Spanish National Research Council.
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Journal ArticleDOI
Changes of Physical Activity and Ultra-Processed Food Consumption in Adolescents from Different Countries during Covid-19 Pandemic: An Observational Study.
María Belén Ruiz-Roso,Patricia de Carvalho Padilha,Diana C. Matilla-Escalante,Paola Brun,Natalia Ulloa,Diofanor Acevedo-Correa,Wilza Arantes Ferreira Peres,Miquel Martorell,Thaís Rangel Bousquet Carrilho,Letícia de Oliveira Cardoso,Fernanda Carrasco-Marín,Katherine Paternina-Sierra,María-Carmen López de Las Hazas,Jhon E. Rodriguez-Meza,Luisa F. Villalba-Montero,Giulia Bernabè,Anthony Pauletto,Xhoajda Taci,Richar Cárcamo-Regla,J. Alfredo Martínez,Alberto Dávalos +20 more
TL;DR: A higher prevalence of inactivity was observed in this population, but reductions of physical activity and habitual ultra-processed consumption during the pandemic were more pronounced in Latin America.
Journal ArticleDOI
Differential absorption and metabolism of hydroxytyrosol and its precursors oleuropein and secoiridoids
María-Carmen López de Las Hazas,Carme Piñol,Alba Macià,Maria-Paz Romero,Anna Pedret,Rosa Solà,Laura Rubió,Maria-José Motilva +7 more
TL;DR: Findings suggest that OLE might be the most suitable precursor of HT for incorporation into foods or nutraceutical formulations and bioavailability based on the urine excretion of HT metabolites was higher.
Journal ArticleDOI
Bovine Milk-Derived Exosomes as a Drug Delivery Vehicle for miRNA-Based Therapy.
Lorena Del Pozo-Acebo,María-Carmen López de Las Hazas,Joao Tomé-Carneiro,Paula Gil-Cabrerizo,Rodrigo San-Cristobal,Rebeca Busto,Almudena García-Ruiz,Alberto Dávalos +7 more
TL;DR: In this paper, exosomes were isolated from raw bovine milk, combining ultracentrifugation and size exclusion chromatography (SEC) methodology, and then loaded with exogenous hsa-miR148a-3p, a highly expressed miRNA in milk exosome.
Journal ArticleDOI
Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells
Úrsula Catalán,María-Carmen López de Las Hazas,Laura Rubió,Sara Fernández-Castillejo,Anna Pedret,Rafael de la Torre,Maria-José Motilva,Rosa Solà +7 more
TL;DR: Physiological HT metabolites, synthetized for the first time by using an intestinal cell model, might be responsible in part for the protection against endothelial dysfunction.
Journal ArticleDOI
Hydroxytyrosol and the Colonic Metabolites Derived from Virgin Olive Oil Intake Induce Cell Cycle Arrest and Apoptosis in Colon Cancer Cells
TL;DR: Results showed that HT and phenylacetic and hydroxyphenylpropionic acids produce cell cycle arrest and promote apoptosis and HT-29 cells were more sensitive to phenol treatments than Caco-2.