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Maria Claudia Irigoyen

Researcher at University of São Paulo

Publications -  248
Citations -  3730

Maria Claudia Irigoyen is an academic researcher from University of São Paulo. The author has contributed to research in topics: Blood pressure & Baroreflex. The author has an hindex of 31, co-authored 246 publications receiving 3239 citations. Previous affiliations of Maria Claudia Irigoyen include Federal University of São Paulo & Universidade Federal de Minas Gerais.

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Cardiovascular and autonomic phenotype of db/db diabetic mice

TL;DR: The results document an age‐related increase in MAP in db/db mice, which can be reduced by antagonism of angiotensin II AT1 receptors, and alterations in autonomic balance and components of the renin–angiotens in system.
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Cholinergic stimulation with pyridostigmine increases heart rate variability and baroreflex sensitivity in rats.

TL;DR: The present results support the concept that cholinergic stimulation with pyridostigmine may become a therapeutic option for vagal dysfunction, and reduced HR variability and baroreflex sensitivity are independent risk factors in heart disease.
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Effects of Resistance Training on Ventricular Function and Hypertrophy in a Rat Model

TL;DR: In this paper, the authors used echocardiography data to investigate changes in ventricular function in rats undergoing resistance training for a period of 1 and 3 months, and found that the increased wall thickness induced by pressure overload was mainly due to an increase in the myocyte cross-sectional area.
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Increased renal GLUT1 abundance and urinary TGF-beta 1 in streptozotocin-induced diabetic rats: implications for the development of nephropathy complicating diabetes.

TL;DR: It is concluded that 45 days of diabetes result in incipient diabetic nephropathy and increased cortical GLUT1 protein abundance, which is speculated to amplify the effects of hyperglycemia in determining higher intracellular glucose in mesangial cells, thereby contributing to diabetes-related kidney damage.