M
Maria Filomena Botelho
Researcher at University of Coimbra
Publications - 209
Citations - 3198
Maria Filomena Botelho is an academic researcher from University of Coimbra. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 25, co-authored 192 publications receiving 2355 citations.
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Journal ArticleDOI
Amniotic membrane: from structure and functions to clinical applications
A.C. Mamede,Maria João Carvalho,Ana M. Abrantes,Mafalda Laranjo,Cláudio J. Maia,Maria Filomena Botelho +5 more
TL;DR: AM is a promoter of epithelialization and is a non-tumorigenic tissue and its use has no ethical problems, and it has been applied in several surgical procedures related to ocular surface reconstruction and the genito-urinary tract, skin, head and neck, among others.
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Lymphatic Uptake of Pulmonary Delivered Radiolabelled Solid Lipid Nanoparticles
Mafalda Videira,Maria Filomena Botelho,Ana C. Santos,Luís F. Gouveia,J. J. Pedroso de Lima,António J. Almeida +5 more
TL;DR: It is indicated that SLN could be effective colloidal carriers for lymphoscintigraphy or therapy upon pulmonary delivery and an important and significant uptake of the radiolabelled SLN into the lymphatics after inhalation, and a high rate of distribution in periaortic, axillar and inguinal lymph nodes.
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The role of vitamins in cancer: a review.
A.C. Mamede,Sónia Dorilde Tavares,Ana M. Abrantes,Joana Trindade,J.M. Maia,Maria Filomena Botelho +5 more
TL;DR: This review will present the work and more relevant conclusions obtained in recent years of investigation about the relationship between vitamins and cancer, namely vitamin A, vitamin B complex, vitamin C, vitamin D, vitamin E, and vitamin K.
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MIA PaCa-2 and PANC-1 – pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors
TL;DR: Those MIA PaCa-2 and PANC-1 cell line phenotype and genotype characteristics that may play a crucial role in pancreatic cancer therapeutic assays, namely neuroendocrine chemotherapy and peptide receptor radionuclide therapy are described.
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Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?
Ana Brito,Marina Ribeiro,Ana M. Abrantes,Ana Salomé Pires,Ricardo Teixo,José Guilherme Tralhão,Maria Filomena Botelho +6 more
TL;DR: This review is focused on the relationship between flavonoids and cancer, with special emphasis on the role of quercetin, which has diverse biological effects, inhibiting multiple enzymes involved in cell proliferation, as well as, in signal transduction pathways.