M
Maria G. Belvisi
Researcher at National Institutes of Health
Publications - 275
Citations - 17371
Maria G. Belvisi is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Sensory nerve & Cholinergic. The author has an hindex of 73, co-authored 269 publications receiving 16021 citations. Previous affiliations of Maria G. Belvisi include Aventis Pharma & AstraZeneca.
Papers
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Journal ArticleDOI
IκB Kinase-2-Independent and -Dependent Inflammation in Airway Disease Models: Relevance of IKK-2 Inhibition to the Clinic
Mark A. Birrell,Sissie Wong,Elizabeth Hardaker,Matthew C. Catley,Kerryn McCluskie,Michael A. Collins,Saleem Haj-Yahia,Maria G. Belvisi +7 more
TL;DR: This is the first study to examine the effect of an IKK-2 inhibitor in well validated models that mimic aspects of the inflammatory lesion evident in diseases such as COPD and may lead to greater understanding of disease pathology and the discovery of novel anti-inflammatory targets.
Journal ArticleDOI
Inhibition of cholinergic neurotransmission in human airways by opioids.
Maria G. Belvisi,C.D. Stretton,Geert Verleden,S. J. L. Ledingham,Magdi H. Yacoub,P. J. Barnes +5 more
TL;DR: It is concluded that mu-opioid agonists inhibit cholinergic neurotransmission in human airways in vitro, and this could have therapeutic potential in the treatment of airway disease.
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Pre-clinical studies in cough research: Role of Transient Receptor Potential (TRP) channels
TL;DR: In vitro and in vivo models that are currently used to further the understanding of the sensory innervation of the respiratory tract, and how these nerves are involved in controlling the cough response are focused on.
Journal ArticleDOI
Bronchial Epithelial Cell-Derived Prostaglandin E2 Dampens the Reactivity of Dendritic Cells
Lotte M. Schmidt,Maria G. Belvisi,Konrad A. Bode,Judith Bauer,Claudia Schmidt,Maria T. Suchy,Dimitrios Tsikas,Jutta Scheuerer,Felix Lasitschka,Herman Josef Gröne,Alexander H. Dalpke +10 more
TL;DR: The results indicate that airway epithelial cell-derived PGE2 contributes to the modulation of DCs under homeostatic conditions.
Journal ArticleDOI
Steroid-resistant Inflammation in a Rat Model of Chronic Obstructive Pulmonary Disease Is Associated with a Lack of Nuclear Factor-κB Pathway Activation
Mark A. Birrell,Sissie Wong,David J Hele,Kerryn McCluskie,Elizabeth Hardaker,Maria G. Belvisi +5 more
TL;DR: This model, in addition to its suitability for testing therapies that may modify existing emphysema, could be useful in the search for new therapies to reduce the steroid-resistant airway inflammation evident in COPD.