Maria Manconi

TL;DR: Results showed that negatively charged liposomes strongly improved newborn pig skin hydration and TRA retention, though no evidence of intact vesicle penetration was found, and may be an interesting carrier for tretinoin in skin disease treatment, when appropriate formulations are used.

TL;DR: Results showed that tretinoin cutaneous delivery is strongly affected by vesicle composition and thermodynamic activity of the drug, and small, negatively charged niosomal formulations, which are saturated with tretinin, have shown to give higher cutaneous drug retention than both liposomes and commercial formulation.

TL;DR: Release data showed that tretinoin delivery is mainly affected by the vesicular structure and that tretsin delivery increased from MLVs to LUVs to SUVs.

TL;DR: In this paper, the effect of liposomal inclusion on the in vitro antiherpetic activity of Artemisia arborescens L. essential oil was investigated, which showed that Artemisia essential oil can be incorporated in good amounts in the prepared vesicular dispersions.

TL;DR: In vivo tests underlined a good effectiveness of curcumin-loaded hyalurosomes to counteract 12-O-tetradecanoilphorbol (TPA)-produced inflammation and injuries, diminishing oedema formation, myeloperoxydase activity and providing an extensive skin reepithelization.