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María Moros

Researcher at University of Zaragoza

Publications -  65
Citations -  2759

María Moros is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Magnetic nanoparticles & Nanoparticle. The author has an hindex of 23, co-authored 57 publications receiving 2156 citations. Previous affiliations of María Moros include Spanish National Research Council & National Research Council.

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Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine

TL;DR: The aim of this review is not only to provide in-depth insights into the different biofunctionalization and characterization methods, but also to give an overview of possibilities and limitations of the available nanoparticles.
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Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms.

TL;DR: The ability to selectively induce apoptotic cell death and to understand the subsequent mechanisms provides the foundations to predict and optimize NP-based photothermal therapy to treat cancer patients suffering from chemo- and radioresistance.
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Taking Advantage of Unspecific Interactions to Produce Highly Active Magnetic Nanoparticle−Antibody Conjugates

TL;DR: The functionalization of MNPs is proposed via a two-steps strategy that takes advantage of the ionic reversible interactions between the Ab and the MNP to make possible the orientation of the Ab on the M NP surface before being attached in an irreversible way via covalent bonds.
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Monosaccharides versus PEG-Functionalized NPs: Influence in the Cellular Uptake

TL;DR: Surprisingly, the glucose-coated NPs described here showed cellular uptake as a result of lipid raft instead of clathrin-mediated cellular internalization and could be one of the first examples of NPs being endocytosed by caveolae that finally end up in the lysosomes.
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Gold-nanoparticles coated with the antimicrobial peptide esculentin-1a(1-21)NH2 as a reliable strategy for antipseudomonal drugs.

TL;DR: This is the first report showing that a covalent binding of a linear AMP via a poly(ethylene glycol) linker to AuNPs highly enhances antipseudomonal activity, preserving the same mode of action of the free peptide, without being harmful.