M
Maria Rosaria Sapienza
Researcher at European Institute of Oncology
Publications - 41
Citations - 917
Maria Rosaria Sapienza is an academic researcher from European Institute of Oncology. The author has contributed to research in topics: Lymphoma & Medicine. The author has an hindex of 15, co-authored 34 publications receiving 735 citations. Previous affiliations of Maria Rosaria Sapienza include University of Bologna.
Papers
More filters
Journal ArticleDOI
Gene expression analysis uncovers similarity and differences among Burkitt lymphoma subtypes
Pier Paolo Piccaluga,Pier Paolo Piccaluga,Giulia De Falco,Manjunath Kustagi,Anna Gazzola,Claudio Agostinelli,Claudio Tripodo,Eleonora Leucci,Anna Onnis,Annalisa Astolfi,Maria Rosaria Sapienza,Cristiana Bellan,Stefano Lazzi,Lynnette K Tumwine,Michael Mawanda,Martin D. Ogwang,Valeria Calbi,Serena Formica,Andrea Califano,Stefano Pileri,Lorenzo Leoncini +20 more
TL;DR: This study studied GEPs of BL subtypes, other B-cell lymphomas, and B lymphocytes and found that all BLs were intimately related to germinal center cells, differing from them for molecules involved in cell proliferation, immune response, and signal transduction.
Journal ArticleDOI
Molecular Profiling Improves Classification and Prognostication of Nodal Peripheral T-Cell Lymphomas: Results of a Phase III Diagnostic Accuracy Study
Pier Paolo Piccaluga,Fabio Fuligni,Antonio De Leo,Clara Bertuzzi,Maura Rossi,Francesco Bacci,Elena Sabattini,Claudio Agostinelli,Anna Gazzola,Maria Antonella Laginestra,Claudia Mannu,Maria Rosaria Sapienza,Sylvia Hartmann,Martin L. Hansmann,Roberto Piva,Javeed Iqbal,John C. Chan,D. D. Weisenburger,Julie M. Vose,Monica Bellei,Massimo Federico,Giorgio Inghirami,Pier Luigi Zinzani,Stefano Pileri +23 more
TL;DR: A phase III diagnostic accuracy study to test the ability of gene expression profiles (GEPs; index test) to identify PTCL subtype supports the usage of an MC as additional tool in the diagnostic workup of nodal P TCL.
Journal ArticleDOI
Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition
Maria Rosaria Sapienza,Fabio Fuligni,Claudio Agostinelli,Claudio Tripodo,Simona Righi,Maria Antonella Laginestra,Alessandro Pileri,Manuela Mancini,Martina Rossi,Francesca Ricci,Anna Gazzola,Federica Melle,Claudia Mannu,Francesca Ulbar,Mario Arpinati,Marco Paulli,Takahiro Maeda,Davide Gibellini,Livio Pagano,Nicola Pimpinelli,Marco Santucci,Lorenzo Cerroni,Carlo M. Croce,Fabio Facchetti,Pier Paolo Piccaluga,Stefano Pileri +25 more
TL;DR: A molecular signature representative of the transcriptional abnormalities of BPDCN is identified and a cellular model proposing a novel therapeutic approach in the setting of this otherwise incurable disease is developed.
Journal ArticleDOI
Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects.
Maria Rosaria Sapienza,Alessandro Pileri,Enrico Derenzini,Federica Melle,Giovanna Motta,Stefano Fiori,Angelica Calleri,Nicola Pimpinelli,Valentina Tabanelli,Stefano Pileri +9 more
TL;DR: The epidemiologic, clinical, diagnostic, molecular, and therapeutic features of BPDCN are thoroughly revised in order to contribute to an up-to-date approach to this tumour that has remained an orphan disease for too long.
Journal ArticleDOI
Pathobiology of hodgkin lymphoma.
Pier Paolo Piccaluga,Claudio Agostinelli,Anna Gazzola,Claudio Tripodo,Francesco Bacci,Elena Sabattini,Maria Teresa Sista,Claudia Mannu,Maria Rosaria Sapienza,Maura Rossi,Maria Antonella Laginestra,Carlo A. Sagramoso-Sacchetti,Simona Righi,Stefano Pileri +13 more
TL;DR: There is complete consensus on the B-cell derivation of the tumor in most cases, and on the relevance of Epstein-Barr virus infection and defective cytokinesis in at least a proportion of patients.