M
Maria Teresa Canciani
Researcher at University of Milan
Publications - 54
Citations - 3519
Maria Teresa Canciani is an academic researcher from University of Milan. The author has contributed to research in topics: Von Willebrand factor & Von Willebrand disease. The author has an hindex of 28, co-authored 54 publications receiving 3293 citations. Previous affiliations of Maria Teresa Canciani include Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.
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Journal ArticleDOI
Changes in health and disease of the metalloprotease that cleaves von Willebrand factor.
P. M. Mannucci,Maria Teresa Canciani,Ileana Forza,Federico Lussana,Antonella Lattuada,Edoardo Rossi +5 more
TL;DR: In this article, the authors evaluated the specificity of low protease plasma levels in the diagnosis of TTP using an enzyme immunoassay, and found that low plasma levels of the vWF cleaving protease are also low in several physiological and pathologic conditions, including decompensated liver cirrhosis, uremia, and acute inflammation.
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Response of Factor VIII/von Willebrand Factor to DDAVP in Healthy Subjects and Patients with Haemophilia A and von Willebrand's Disease
TL;DR: It is shown that the consistency of the VIII:C response tends to decrease when repeated doses are given to healthy subjects, and this study shows that the response appears to be more prolonged in haemophiliacs.
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ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
Flora Peyvandi,Silvia Lavoretano,R. Palla,Hendrik B. Feys,Karen Vanhoorelbeke,Tullia Battaglioli,Carla Valsecchi,Maria Teresa Canciani,Fabrizio Fabris,Samo Zver,Marienn Réti,Danijela Mikovic,Mehran Karimi,Gaetano Giuffrida,Luca Laurenti,Pier Mannuccio Mannucci +15 more
TL;DR: Survivors of an acute episode of acquired thrombotic throm bocytopenic purpura with severely reduced levels of ADAMTS13 and/or with anti-ADAMts13 antibodies during remission have an approximately three-fold greater likelihood of developing another episode of thrommosis than patients with higher protease activity and no antibody.
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Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients.
Augusto B. Federici,Pier Mannuccio Mannucci,Giancarlo Castaman,Luciano Baronciani,Paolo Bucciarelli,Maria Teresa Canciani,Alessandro Pecci,Peter J. Lenting,Philip G. de Groot +8 more
TL;DR: In this paper, the authors evaluated the prevalence and clinical and molecular predictors of thrombocytopenia in a cohort of 67 VWD2B patients from 38 unrelated families characterized by van Willebrand factor mutations.
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von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.
Giuseppe Remuzzi,Miriam Galbusera,Marina Noris,Maria Teresa Canciani,Erica Daina,Elena Bresin,Silvia Contaretti,Jessica Caprioli,Sara Gamba,Piero Ruggenenti,Norberto Perico,Pier Mannuccio Mannucci +11 more