M
Mariana Castanheira
Researcher at Federal University of São Paulo
Publications - 386
Citations - 17664
Mariana Castanheira is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Broth microdilution & Medicine. The author has an hindex of 64, co-authored 314 publications receiving 14422 citations.
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Journal ArticleDOI
Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses
Shawn R. Lockhart,Kizee A. Etienne,Snigdha Vallabhaneni,Joveria Farooqi,Anuradha Chowdhary,Nelesh P. Govender,Arnaldo Lopes Colombo,Belinda Calvo,Christina A. Cuomo,Christopher A. Desjardins,Elizabeth L. Berkow,Mariana Castanheira,Rindidzani E. Magobo,Kauser Jabeen,Rana Jawad Asghar,Jacques F. Meis,Brendan R Jackson,Tom Chiller,Anastasia P. Litvintseva +18 more
TL;DR: Candida auris is an emerging healthcare-associated pathogen associated with high mortality, and WGS analysis suggests nearly simultaneous, and recent, independent emergence of different clonal populations on 3 continents.
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Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations
Barbara D. Alexander,Melissa D. Johnson,Christopher D. Pfeiffer,Cristina Jiménez-Ortigosa,Jelena Catania,Rachel Booker,Mariana Castanheira,Shawn A. Messer,David S. Perlin,Michael A. Pfaller +9 more
TL;DR: Echinocandin resistance is increasing, including among FLC-resistant isolates, and the importance of knowing the local epidemiology and resistance patterns for Candida within institutions and susceptibility testing of echinocands for C. glabrata to guide therapeutic decision making is underscored.
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Escherichia coli Sequence Type ST131 as the Major Cause of Serious Multidrug-Resistant E. coli Infections in the United States
James R. Johnson,Brian Duncan Johnston,Connie Clabots,Michael A. Kuskowski,Mariana Castanheira +4 more
TL;DR: In this paper, the CTX-M-15 extended-spectrum beta-lactamase-associated Escherichia coli sequence type ST131 (O25:H4) has emerged internationally as a multidrug-resistant pathogen but has received little attention in the United States.
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Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997-2016.
TL;DR: EC-R and FLU-R remain uncommon among contemporary Candida isolates; however, a slow and steady emergence of resistance to both antifungal classes was observed in C. glabrata and C. tropicalis isolates.
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Early Dissemination of NDM-1- and OXA-181-Producing Enterobacteriaceae in Indian Hospitals: Report from the SENTRY Antimicrobial Surveillance Program, 2006-2007
Mariana Castanheira,Lalitagauri M. Deshpande,Dilip Mathai,Jan M. Bell,Ronald N. Jones,Rodrigo E. Mendes +5 more
TL;DR: Among 39 carbapenem-resistant Enterobacteriaceae isolated in 2006 and 2007 in India, 15 strains carried bla NDM-1 and 10 harbored a gene encoding a variant of the carbapENemase OXA-48, named bla OXa-181, which was disseminated in Indian health care facilities as early as 2006.