M
Maribel Paredes Olotegui
Publications - 5
Citations - 812
Maribel Paredes Olotegui is an academic researcher. The author has contributed to research in topics: Subclinical infection & Cognitive development. The author has an hindex of 5, co-authored 5 publications receiving 549 citations.
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Journal ArticleDOI
The MAL-ED Study: A Multinational and Multidisciplinary Approach to Understand the Relationship Between Enteric Pathogens, Malnutrition, Gut Physiology, Physical Growth, Cognitive Development, and Immune Responses in Infants and Children Up to 2 Years of Age in Resource-Poor Environments
Angel Mendez Acosta,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Zulfiqar A Bhutta,Shahida Qureshi,Sadia Shakoor,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Ladaporn Bodhidatta,Carl J. Mason,Sudhir Babji,Anuradha Bose,Sushil John,Gagandeep Kang,Beena Kurien,Jayaprakash Muliyil,Mohan Venkata Raghava,Anup Ramachandran,Anuradha Rose,William Pan,Ramya Ambikapathi,Danny Carreon,Vivek Charu,Leyfou Dabo,Viyada Doan,Jhanelle Graham,Christel Hoest,Stacey Knobler,Dennis Lang,Benjamin J.J. McCormick,Monica McGrath,Mark A. Miller,Archana Mohale,Gaurvika M. L. Nayyar,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Jessica C. Seidman,Vivian Ota Wang,Rebecca Blank,Michael Gottlieb,Karen H. Tountas,Caroline Amour,Estomih Mduma,Tahmeed Ahmed,AM Shamsir Ahmed,Mondol Dinesh,Fahmida Tofail,Rashidul Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Robert E. Black,Laura E. Caulfield,William Checkley,Ping Chen,Margaret Kosek,Gwenyth O. Lee,Pablo Peñataro Yori,Laura E. Murray-Kolb,Barbara A. Schaefer,Laura L. Pendergast,Cláudia B. Abreu,Alexandre Havt Bindá,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Aldo A. M. Lima,Noélia L. Lima,Ila F. N. Lima,Bruna Leal Lima Maciel,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Erling Svensen,Strand Tor,Crystal L. Patil,Pascal O. Bessong,Cloupas Mahopo,Angelina Mapula,Cebisa Nesamvuni,Emanuel Nyathi,Amidou Samie,Leah J. Barrett,Jean Gratz,Richard Guerrant,Eric R. Houpt,Liz Olmsted,William A. Petri,James A Platts-Mills,Rebecca J. Scharf,Binob Shrestha,Sanjaya K. Shrestha +108 more
TL;DR: The hypothesis is that enteropathogen infection contributes to undernutrition by causing intestinal inflammation and/or by altering intestinal barrier and absorptive function, and it is further postulated that this leads to growth faltering and deficits in cognitive development.
Journal ArticleDOI
Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: Longitudinal analysis of results from the MAL-ED cohort study
Elizabeth T. Rogawski,Jie Liu,James A Platts-Mills,Furqan Kabir,Paphavee Lertsethtakarn,Mery Siguas,Shaila S Khan,Ira Praharaj,Arinao Murei,Rosemary Nshama,Buliga Mujaga,Alexandre Havt,Irene A Maciel,Darwin J. Operario,Mami Taniuchi,Jean Gratz,Suzanne Stroup,James H Roberts,Adil Kalam,Fatima Aziz,Shahida Qureshi,M Ohedul Islam,Pimmada Sakpaisal,Sasikorn Silapong,Pablo Peñataro Yori,Revathi Rajendiran,Blossom Benny,Monica McGrath,Monica McGrath,Jessica C. Seidman,Dennis Lang,Michael Gottlieb,Richard L. Guerrant,Aldo A. M. Lima,José Paulo Gagliardi Leite,Amidou Samie,Pascal O. Bessong,Nicola Page,Ladaporn Bodhidatta,Carl J. Mason,Sanjaya K. Shrestha,Sanjaya K. Shrestha,Ireen Kiwelu,Estomih Mduma,Najeeha Talat Iqbal,Zulfiqar A Bhutta,Tahmeed Ahmed,Rashidul Haque,Gagandeep Kang,Margaret Kosek,Eric R. Houpt,Angel Mendez Acosta,Rosa Burga,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Muneera A. Rasheed,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Binob Shrestha,Bishnu Bahadur Rayamajhi,Tor A. Strand,Geetha Ammu,Sudhir Babji,Anuradha Bose,Ajila T. George,Dinesh Hariraju,M. Steffi Jennifer,Sushil John,Shiny Kaki,Priyadarshani Karunakaran,Beena Koshy,Robin P. Lazarus,Jayaprakash Muliyil,Preethi Ragasudha,Mohan Venkata Raghava,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,Karthikeyan Ramanujam,Anuradha Rose,Reeba Roshan,Srujan Lam Sharma,Shanmuga Sundaram,Rahul J. Thomas,William Pan,Ramya Ambikapathi,J. Daniel Carreon,Viyada Doan,Christel Hoest,Stacey Knobler,Mark A. Miller,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Karen H. Tountas,Erling Svensen,Caroline Amour,Eliwaza Bayyo,Regisiana Mvungi,John M. Pascal,Ladislaus Blacy Yarrot,Leah J. Barrett,Rebecca Dillingham,William A. Petri,Rebecca J. Scharf,AM Shamsir Ahmed,Ashraful Alam,Umma Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Dinesh Mondal,Baitun Nahar,Fahmida Tofail,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Aubrey Bauck,Robert E. Black,Laura E. Caulfield,William Checkley,Gwenyth O. Lee,Kerry Schulze,Samuel Scott,Laura E. Murray-Kolb,A. Catharine Ross,Barbara A. Schaefer,Suzanne Simons,Laura L. Pendergast,Cláudia B. Abreu,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Noélia L. Lima,Ila F. N. Lima,Bruna L L Maciel,Pedro Hqs Medeiros,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Rosa Ms Mota,Crystal L. Patil,Cloupas Mahopo,Angelina Maphula,Emanuel Nyathi +157 more
TL;DR: Subclinical infection and quantity of pathogens, particularly Shigella, enteroaggregative E coli, Campylobacter, and Giardia, had a substantial negative association with linear growth, which was sustained during the first 2 years of life, and in some cases, to 5 years.
Journal ArticleDOI
Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.
James A Platts-Mills,Jie Liu,Elizabeth T. Rogawski,Furqan Kabir,Paphavee Lertsethtakarn,Mery Siguas,Shaila S Khan,Ira Praharaj,Arinao Murei,Rosemary Nshama,Buliga Mujaga,Alexandre Havt,Irene A Maciel,Timothy L. McMurry,Darwin J. Operario,Mami Taniuchi,Jean Gratz,Suzanne Stroup,James H Roberts,Adil Kalam,Fatima Aziz,Shahida Qureshi,M Ohedul Islam,Pimmada Sakpaisal,Sasikorn Silapong,Pablo Peñataro Yori,Revathi Rajendiran,Blossom Benny,Monica McGrath,Monica McGrath,Benjamin J.J. McCormick,Jessica C. Seidman,Dennis Lang,Michael Gottlieb,Richard L. Guerrant,Aldo A. M. Lima,José Paulo Gagliardi Leite,Amidou Samie,Pascal O. Bessong,Nicola Page,Ladaporn Bodhidatta,Carl J. Mason,Sanjaya K. Shrestha,Sanjaya K. Shrestha,Ireen Kiwelu,Estomih Mduma,Najeeha Talat Iqbal,Zulfiqar A Bhutta,Tahmeed Ahmed,Rashidul Haque,Gagandeep Kang,Margaret Kosek,Eric R. Houpt,Angel Mendez Acosta,Rosa Burga,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Muneera A. Rasheed,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Binob Shrestha,Bishnu Bahadur Rayamajhi,Tor A. Strand,Geetha Ammu,Sudhir Babji,Anuradha Bose,Ajila T. George,Dinesh Hariraju,M. Steffi Jennifer,Sushil John,Shiny Kaki,Priyadarshani Karunakaran,Beena Koshy,Robin P. Lazarus,Jayaprakash Muliyil,Preethi Ragasudha,Mohan Venkata Raghava,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,Karthikeyan Ramanujam,Anuradha Rose,Reeba Roshan,Srujan Lam Sharma,Shanmuga Sundaram,Rahul J. Thomas,William Pan,Ramya Ambikapathi,J. Daniel Carreon,Viyada Doan,Christel Hoest,Stacey Knobler,Mark A. Miller,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Karen H. Tountas,Erling Svensen,Caroline Amour,Eliwaza Bayyo,Regisiana Mvungi,John M. Pascal,Ladislaus Blacy Yarrot,Leah J. Barrett,Rebecca Dillingham,William A. Petri,Rebecca J. Scharf,AM Shamsir Ahmed,Ashraful Alam,Umma Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Dinesh Mondal,Baitun Nahar,Fahmida Tofail,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Aubrey Bauck,Robert E. Black,Laura E. Caulfield,William Checkley,Gwenyth O. Lee,Kerry Schulze,Samuel Scott,Laura E. Murray-Kolb,A. Catharine Ross,Barbara A. Schaefer,Suzanne Simons,Laura L. Pendergast,Cláudia B. Abreu,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Noélia L. Lima,Ila F. N. Lima,Bruna L L Maciel,Pedro Hqs Medeiros,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Rosa Ms Mota,Crystal L. Patil,Cloupas Mahopo,Angelina Maphula,Emanuel Nyathi +159 more
TL;DR: Quantitative molecular diagnostics improved estimates of pathogen-specific burdens of childhood diarrhoea in the community setting and created aetiology prediction scores using clinical characteristics that could improve the management of diarrhoee in these low-resource settings.
Early childhood cognitive development is affected by interactions among illness, diet, enteropathogens and the home environment: Findings from the MAL-ED birth cohort study
Laura E. Murray-Kolb,Angel Mendez Acosta,RR De Burga,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Pinedo,Salas,Trigoso,Angel Orbe Vasquez,Imran Ahmed,Dewan S. Alam,Asad Ali,Zulfiqar A Bhutta,Shahida Qureshi,Muneera A. Rasheed,Sajid Bashir Soofi,Ali Turab,Akm Zaidi,Ladaporn Bodhidatta,Carl J. Mason,Sudhir Babji,Anuradha Bose,Ajila T. George,Dinesh Hariraju,Jennifer,Sushil John,Shiny Kaki,Gagandeep Kang,Priyadarshani Karunakaran,Beena Koshy,Robin P. Lazarus,Jayaprakash Muliyil,Mohan Venkata Raghava,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,Karthikeyan Ramanujam,Reeba Roshan,Srujan Lam Sharma,Shanmuga Sundaram,Rahul J. Thomas,William Pan,Ramya Ambikapathi,JD Carreon,Charu,Doan,Jhanelle Graham,Christel Hoest,Stacey Knobler,Lang,Bjj McCormick,Monica McGrath,Mark A. Miller,Archana Mohale,Gaurvika M. L. Nayyar,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Jessica C. Seidman,Wang,Rebecca Blank,Michael Gottlieb,Karen H. Tountas,Caroline Amour,Eliwaza Bayyo,Estomih R. Mduma,Regisiana Mvungi,Rosemary Nshama,John M. Pascal,Buliga Mujaga Swema,Ladislaus Blacy Yarrot,Tahmeed Ahmed,Ams Ahmed,Rashidul Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Dinesh Mondal,Fahmida Tofail,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Aubrey Bauck,Robert E. Black,Laura E. Caulfield,William Checkley,Margaret Kosek,Gwenyth O. Lee,Kerry Schulze,Pablo Peñataro Yori,A. Catharine Ross,Barbara A. Schaefer,Suzanne Simons,Laura L. Pendergast,Cláudia B. Abreu,H. Costa +97 more
Journal ArticleDOI
Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: results from the MAL-ED study.
Benjamin J.J. McCormick,Laura E. Murray-Kolb,Gwenyth O. Lee,Kerry Schulze,A. Catharine Ross,Aubrey Bauck,Aldo A. M. Lima,Bruna Leal Lima Maciel,Margaret Kosek,Jessica C. Seidman,Ramya Ambikapathi,Anuradha Bose,Sushil John,Gagandeep Kang,Ali Turab,Estomih Mduma,Pascal O. Bessong,Sanjaya K. Shrestra,Tahmeed Ahmed,Mustafa Mahfuz,Maribel Paredes Olortegui,Zulfiqar A Bhutta,Laura E. Caulfield,Angel Mendez Acosta,Rosa Burga,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Mery Siguas Salas,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Zulfiqar A. Bhutta,Shahida Qureshi,Muneera A. Rasheed,Sajid Bashir Soofi,Anita K. M. Zaidi,Ladaporn Bodhidatta,Carl J. Mason,Sudhir Babji,Ajila T. George,Dinesh Hariraju,M. Steffi Jennifer,Shiny Kaki,Priyadarshani Karunakaran,Beena Koshy,Robin P. Lazarus,Jayaprakash Muliyil,Mohan Venkata Raghava,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,Karthikeyan Ramanujam,Reeba Roshan,Srujan Lam Sharma,Shanmuga Sundaram,Rahul J. Thomas,William Pan,William Pan,J. Daniel Carreon,Vivek Charu,Viyada Doan,Jhanelle Graham,Christel Hoest,Stacey Knobler,Dennis Lang,Monica McGrath,Mark A. Miller,Archana Mohale,Gaurvika M. L. Nayyar,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Vivian Ota Wang,Rebecca Blank,Michael Gottlieb,Karen H. Tountas,Caroline Amour,Eliwaza Bayyo,Estomih R. Mduma,Regisiana Mvungi,Rosemary Nshama,John M. Pascal,Buliga Mujaga Swema,Ladislaus Blacy Yarrot,AM Shamsir Ahmed,Rashidul Haque,Iqbal Hossain,M Munirul Islam,Dinesh Mondal,Fahmida Tofail,Ram Krishna Chandyo,Prakash S. Shrestha,Rita Shrestha,Manjeswori Ulak,Robert E. Black,William Checkley,William Checkley,Pablo Peñataro Yori,Barbara A. Schaefer,Barbara A. Schaefer,Suzanne Simons,Laura L. Pendergast,Cláudia B. Abreu,H. Costa,Alessandra Di Moura,José Q. Filho,José Q. Filho,Alexandre Havt,Álvaro M. Leite,Noélia L. Lima,Ila F. N. Lima,Pedro H. Q. S. Medeiros,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Rosa Maria Salani Mota,Crystal L. Patil,Cloupas Mahopo,Angelina Maphula,Emanuel Nyathi,Amidou Samie,Leah J. Barrett,Rebecca Dillingham,Jean Gratz,Richard L. Guerrant,Eric R. Houpt,William A. Petri,James A Platts-Mills,Rebecca J. Scharf,Binob Shrestha,Sanjaya K. Shrestha,Tor A. Strand,Erling Svensen,Erling Svensen +139 more
TL;DR: Inverse associations between nutrient densities and micronutrient deficiency largely disappeared after adjustment for EED, suggesting that EED mediates these associations.