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Benjamin J.J. McCormick
Researcher at National Institutes of Health
Publications - 51
Citations - 2472
Benjamin J.J. McCormick is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Diarrhea & Medicine. The author has an hindex of 19, co-authored 45 publications receiving 1863 citations. Previous affiliations of Benjamin J.J. McCormick include Scottish Agricultural College & John E. Fogarty International Center.
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Journal ArticleDOI
Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED).
James A Platts-Mills,Sudhir Babji,Ladaporn Bodhidatta,Jean Gratz,Jean Gratz,Rashidul Haque,Alexandre Havt,Benjamin J.J. McCormick,Monica McGrath,Maribel Paredes Olortegui,Amidou Samie,Sadia Shakoor,Dinesh Mondal,Ila Fn Lima,Dinesh Hariraju,Bishnu Bahadur Rayamajhi,Shahida Qureshi,Furqan Kabir,Pablo Peñataro Yori,Brenda Mufamadi,Caroline Amour,J. Daniel Carreon,Stephanie A. Richard,Dennis Lang,Pascal O. Bessong,Esto Mduma,Tahmeed Ahmed,Aldo A. M. Lima,Carl J. Mason,Anita K. M. Zaidi,Zulfiqar A Bhutta,Margaret Kosek,Richard L. Guerrant,Michael Gottlieb,Mark A. Miller,Gagandeep Kang,Eric R. Houpt +36 more
TL;DR: The findings suggest that although single-pathogen strategies have an important role in the reduction of the burden of severe diarrhoea disease, the effect of such interventions on total diarrhoeal incidence at the community level might be limited.
Journal ArticleDOI
The MAL-ED Study: A Multinational and Multidisciplinary Approach to Understand the Relationship Between Enteric Pathogens, Malnutrition, Gut Physiology, Physical Growth, Cognitive Development, and Immune Responses in Infants and Children Up to 2 Years of Age in Resource-Poor Environments
Angel Mendez Acosta,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Zulfiqar A Bhutta,Shahida Qureshi,Sadia Shakoor,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Ladaporn Bodhidatta,Carl J. Mason,Sudhir Babji,Anuradha Bose,Sushil John,Gagandeep Kang,Beena Kurien,Jayaprakash Muliyil,Mohan Venkata Raghava,Anup Ramachandran,Anuradha Rose,William Pan,Ramya Ambikapathi,Danny Carreon,Vivek Charu,Leyfou Dabo,Viyada Doan,Jhanelle Graham,Christel Hoest,Stacey Knobler,Dennis Lang,Benjamin J.J. McCormick,Monica McGrath,Mark A. Miller,Archana Mohale,Gaurvika M. L. Nayyar,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Jessica C. Seidman,Vivian Ota Wang,Rebecca Blank,Michael Gottlieb,Karen H. Tountas,Caroline Amour,Estomih Mduma,Tahmeed Ahmed,AM Shamsir Ahmed,Mondol Dinesh,Fahmida Tofail,Rashidul Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Robert E. Black,Laura E. Caulfield,William Checkley,Ping Chen,Margaret Kosek,Gwenyth O. Lee,Pablo Peñataro Yori,Laura E. Murray-Kolb,Barbara A. Schaefer,Laura L. Pendergast,Cláudia B. Abreu,Alexandre Havt Bindá,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Aldo A. M. Lima,Noélia L. Lima,Ila F. N. Lima,Bruna Leal Lima Maciel,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Erling Svensen,Strand Tor,Crystal L. Patil,Pascal O. Bessong,Cloupas Mahopo,Angelina Mapula,Cebisa Nesamvuni,Emanuel Nyathi,Amidou Samie,Leah J. Barrett,Jean Gratz,Richard Guerrant,Eric R. Houpt,Liz Olmsted,William A. Petri,James A Platts-Mills,Rebecca J. Scharf,Binob Shrestha,Sanjaya K. Shrestha +108 more
TL;DR: The hypothesis is that enteropathogen infection contributes to undernutrition by causing intestinal inflammation and/or by altering intestinal barrier and absorptive function, and it is further postulated that this leads to growth faltering and deficits in cognitive development.
Journal ArticleDOI
Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.
James A Platts-Mills,Jie Liu,Elizabeth T. Rogawski,Furqan Kabir,Paphavee Lertsethtakarn,Mery Siguas,Shaila S Khan,Ira Praharaj,Arinao Murei,Rosemary Nshama,Buliga Mujaga,Alexandre Havt,Irene A Maciel,Timothy L. McMurry,Darwin J. Operario,Mami Taniuchi,Jean Gratz,Suzanne Stroup,James H Roberts,Adil Kalam,Fatima Aziz,Shahida Qureshi,M Ohedul Islam,Pimmada Sakpaisal,Sasikorn Silapong,Pablo Peñataro Yori,Revathi Rajendiran,Blossom Benny,Monica McGrath,Monica McGrath,Benjamin J.J. McCormick,Jessica C. Seidman,Dennis Lang,Michael Gottlieb,Richard L. Guerrant,Aldo A. M. Lima,José Paulo Gagliardi Leite,Amidou Samie,Pascal O. Bessong,Nicola Page,Ladaporn Bodhidatta,Carl J. Mason,Sanjaya K. Shrestha,Sanjaya K. Shrestha,Ireen Kiwelu,Estomih Mduma,Najeeha Talat Iqbal,Zulfiqar A Bhutta,Tahmeed Ahmed,Rashidul Haque,Gagandeep Kang,Margaret Kosek,Eric R. Houpt,Angel Mendez Acosta,Rosa Burga,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Muneera A. Rasheed,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Binob Shrestha,Bishnu Bahadur Rayamajhi,Tor A. Strand,Geetha Ammu,Sudhir Babji,Anuradha Bose,Ajila T. George,Dinesh Hariraju,M. Steffi Jennifer,Sushil John,Shiny Kaki,Priyadarshani Karunakaran,Beena Koshy,Robin P. Lazarus,Jayaprakash Muliyil,Preethi Ragasudha,Mohan Venkata Raghava,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,Karthikeyan Ramanujam,Anuradha Rose,Reeba Roshan,Srujan Lam Sharma,Shanmuga Sundaram,Rahul J. Thomas,William Pan,Ramya Ambikapathi,J. Daniel Carreon,Viyada Doan,Christel Hoest,Stacey Knobler,Mark A. Miller,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Karen H. Tountas,Erling Svensen,Caroline Amour,Eliwaza Bayyo,Regisiana Mvungi,John M. Pascal,Ladislaus Blacy Yarrot,Leah J. Barrett,Rebecca Dillingham,William A. Petri,Rebecca J. Scharf,AM Shamsir Ahmed,Ashraful Alam,Umma Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Dinesh Mondal,Baitun Nahar,Fahmida Tofail,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Aubrey Bauck,Robert E. Black,Laura E. Caulfield,William Checkley,Gwenyth O. Lee,Kerry Schulze,Samuel Scott,Laura E. Murray-Kolb,A. Catharine Ross,Barbara A. Schaefer,Suzanne Simons,Laura L. Pendergast,Cláudia B. Abreu,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Noélia L. Lima,Ila F. N. Lima,Bruna L L Maciel,Pedro Hqs Medeiros,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Rosa Ms Mota,Crystal L. Patil,Cloupas Mahopo,Angelina Maphula,Emanuel Nyathi +159 more
TL;DR: Quantitative molecular diagnostics improved estimates of pathogen-specific burdens of childhood diarrhoea in the community setting and created aetiology prediction scores using clinical characteristics that could improve the management of diarrhoee in these low-resource settings.
Journal ArticleDOI
Causal Pathways from Enteropathogens to Environmental Enteropathy: Findings from the MAL-ED Birth Cohort Study.
Margaret Kosek,Tahmeed Ahmed,Zulfiquar Bhutta,Laura E. Caulfield,Richard Guerrant,Eric R. Houpt,Gagandeep Kang,Margaret Kosek,Gwenyth O. Lee,Aldo A. M. Lima,Benjamin J.J. McCormick,James A Platts-Mills,Jessica C. Seidman,Rebecca R. Blank,Michael Gottlieb,Stacey Knobler,Dennis Lang,Mark A. Miller,Karen H. Tountas,Zulfiqar A Bhutta,William Checkley,William Checkley,Richard L. Guerrant,Carl J. Mason,Laura E. Murray-Kolb,William A. Petri,Jessica C. Seidman,Pascal O. Bessong,Rashidul Haque,Sushil John,Aldo Am Lima,Estomih Mduma,Reinaldo B. Oriá,Prakash S. Shrestha,Sanjaya K. Shrestha,Erling Svensen,Erling Svensen,Anita K. M. Zaidi,Cláudia B. Abreu,Angel Mendez Acosta,Imran Ahmed,AM Shamsir Ahmed,Asad Ali,Ramya Ambikapathi,Leah J. Barrett,Aubrey Bauck,Eliwaza Bayyo,Ladaporn Bodhidatta,Anuradha Bose,J. Daniel Carreon,Ram Krishna Chandyo,Vivek Charu,H. Costa,Rebecca Dillingham,Alessandra Di Moura,Viyada Doan,José Q. Filho,José Q. Filho,Jhanelle Graham,Christel Hoest,Iqbal Hossain,M Munirul Islam,M. Steffi Jennifer,Shiny Kaki,Beena Koshy,Álvaro M. Leite,Noélia L. Lima,Bruna L L Maciel,Mustafa Mahfuz,Cloupas Mahopo,Angelina Maphula,Monica McGrath,Archana Mohale,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Jayaprakash Muliyil,Regisiana Mvungi,Gaurvika M. L. Nayyar,Emanuel Nyathi,Maribel Paredes Olortegui,Reinaldo Oria,Angel Orbe Vasquez,William Pan,William Pan,John M. Pascal,Crystal L. Patil,Laura L. Pendergast,Silvia Rengifo Pinedo,Stephanie Psaki,Mohan Venkata Raghava,Karthikeyan Ramanujam,Muneera A. Rasheed,Zeba A Rasmussen,Stephanie A. Richard,Anuradha Rose,Reeba Roshan,Barbara A. Schaefer,Barbara A. Schaefer,Rebecca J. Scharf,Srujan Lam Sharma,Binob Shrestha,Rita Shrestha,Suzanne Simons,Alberto M. Soares,Rosa Maria Salani Mota,Sajid Bashir Soofi,Tor A. Strand,Tor A. Strand,Fahmida Tofail,Rahul J. Thomas,Ali Turab,Manjeswori Ulak,Vivian Ota Wang,Ladislaus Blacy Yarrot,Pablo Peñataro Yori,Didar Alam,Caroline Amour,Cesar Banda Chavez,Sudhir Babji,Rosa Burga,Julian Torres Flores,Jean Gratz,Ajila T. George,Dinesh Hariraju,Alexandre Havt,Priyadarshani Karunakaran,Robin P. Lazarus,Ila F. N. Lima,Dinesh Mondal,Pedro H. Q. S. Medeiros,Rosemary Nshama,Josiane da Silva Quetz,Shahida Qureshi,Sophy Raju,Anup Ramachandran,Rakhi Ramadas,A. Catharine Ross,Mery Siguas Salas,Amidou Samie,Kerry Schulze,E. Shanmuga Sundaram,Buliga Mujaga Swema,Dixner Rengifo Trigoso +142 more
TL;DR: The MAL-ED study represents a novel analytical framework and explicitly evaluates multiple putative EE pathways in combination and using an unprecedented quantity of data to demonstrate that enteric infection alters both fecal markers of inflammation and permeability.
Journal ArticleDOI
Epidemiology and Impact of Campylobacter Infection in Children in 8 Low-Resource Settings: Results From the MAL-ED Study.
Caroline Amour,Jean Gratz,Estomih Mduma,Erling Svensen,Elizabeth T. Rogawski,Monica McGrath,Jessica C. Seidman,Benjamin J.J. McCormick,Sanjaya K. Shrestha,Amidou Samie,Mustafa Mahfuz,Shahida Qureshi,Aneeta Hotwani,Sudhir Babji,Dixner Rengifo Trigoso,Aldo A. M. Lima,Ladaporn Bodhidatta,Pascal O. Bessong,Tahmeed Ahmed,Sadia Shakoor,Gagandeep Kang,Margaret Kosek,Richard L. Guerrant,Dennis Lang,Michael Gottlieb,Eric R. Houpt,James A Platts-Mills +26 more
TL;DR: A association between Campylobacter and linear growth shortfalls and both increased intestinal permeability and intestinal and systemic inflammation is demonstrated and potential interventions are identified.