M
Maribel Rodriguez-Torres
Researcher at San Juan Bautista School of Medicine
Publications - 138
Citations - 13678
Maribel Rodriguez-Torres is an academic researcher from San Juan Bautista School of Medicine. The author has contributed to research in topics: Ribavirin & Hepatitis C. The author has an hindex of 44, co-authored 137 publications receiving 13171 citations. Previous affiliations of Maribel Rodriguez-Torres include Consejo Nacional de Ciencia y Tecnología & Pontifical Catholic University of Puerto Rico.
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Journal ArticleDOI
A phase 2 study of filibuvir in combination with pegylated IFN alfa and ribavirin for chronic HCV.
Maribel Rodriguez-Torres,Eric M. Yoshida,Patrick Marcellin,Subasree Srinivasan,Vivek S. Purohit,Cunshan Wang,Jennifer Hammond +6 more
TL;DR: The addition of filibuvir to pegIFN/ribavirin improved on-treatment virologic response parameters, but this did not translate into improved SVR rates due to a high rate ofVirologic relapse following completion of therapy.
Journal ArticleDOI
1056 mk-7009 significantly improves rapid viral response (rvr) in combination with pegylated interferon alfa-2a and ribavirin in patients with chronic hepatitis c (chc) genotype 1 infection
Michael P. Manns,E.J. Gane,Maribel Rodriguez-Torres,Albrecht Stoehr,C.-T. Yeh,R. Wiedmann,Peggy Hwang,E. Quirk,J. Silber,A. Lee +9 more
TL;DR: MK-7009 Significantly Improves Rapid Viral Response (RVR) in Combination with Pegylated Interferon Alfa-2a and Ribavirin in Patients with Chronic Hepatitis C Genotype 1 Infection.
Journal ArticleDOI
Optimized threshold for serum HCV RNA to predict treatment outcomes in hepatitis C patients receiving peginterferon alfa-2a/ribavirin.
Stefan Zeuzem,Maribel Rodriguez-Torres,K. Rajender Reddy,Patrick Marcellin,Moisés Diago,Antonio Craxì,Paul J. Pockros,M. Rizzetto,David I. Bernstein,Mitchell L. Shiffman,A. Lin,Fernando Tatsch,Stephanos J. Hadziyannis +12 more
TL;DR: Improved the threshold for differentiating low and high viral load by fitting semiparametric generalized additive logistic regression models to the data and constructing receiver operating characteristics curves and finding a threshold HCV RNA level of 400 000 IU/mL is optimal for Differentiating high and low probability of SVR.
Journal ArticleDOI
Peginterferon α-2a plus ribavirin in Latino and Non-Latino Whites with HCV genotype 1: Histologic outcomes and tolerability from the LATINO Study.
Luis A. Balart,Mauricio Lisker-Melman,Fayez M. Hamzeh,Ambrose Kwok,Ellen Lentz,Maribel Rodriguez-Torres +5 more
TL;DR: Significant proportions of patients in both groups had Histologic response to peginterferon α-2a plus ribavirin, however, histologic response was higher in non-Latinos than in Latinos regardless of virologic response.
Journal ArticleDOI
Interferon γ–Induced Protein10 Kinetics in Treatment-Naive Versus Treatment-Experienced Patients Receiving Interferon-Free Therapy for Hepatitis C Virus Infection: Implications for the Innate Immune Response
Jennifer C. Lin,François Habersetzer,Maribel Rodriguez-Torres,Nezam H. Afdhal,Eric Lawitz,Matthew Paulson,Yanni Zhu,Gangadharan Mani Subramanian,John G. McHutchison,Mark S. Sulkowski,David L. Wyles,Robert T. Schooley +11 more
TL;DR: Interferon γ-induced protein 10 levels may be a surrogate marker of the rate of intracellular viral replication complex decay.