M
Marie A. Iannone
Researcher at Research Triangle Park
Publications - 31
Citations - 1833
Marie A. Iannone is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Adenosine & Receptor. The author has an hindex of 18, co-authored 29 publications receiving 1810 citations. Previous affiliations of Marie A. Iannone include GlaxoSmithKline.
Papers
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Journal ArticleDOI
Multiplexed microsphere-based flow cytometric assays.
TL;DR: The speed, sensitivity, and accuracy of flow cytometric detection of multiple binding events measured in the same small volume have the potential to replace many clinical diagnostic and research methods and deliver data on hundreds of analytes simultaneously.
Journal ArticleDOI
Multiplexed single nucleotide polymorphism genotyping by oligonucleotide ligation and flow cytometry.
Marie A. Iannone,J. David Taylor,Jingwen Chen,May-Sung Li,Philip Rivers,Kimberly A. Slentz-Kesler,Michael P. Weiner +6 more
TL;DR: Multiplexed SNP genotyping by OLA with flow cytometric analysis of fluorescent microspheres is an accurate and rapid method for the analysis of SNPs.
Journal ArticleDOI
A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension.
Jingwen Chen,Marie A. Iannone,May-Sung Li,J. David Taylor,Philip Rivers,Anita J. Nelsen,Kimberly A. Slentz-Kesler,Allen Roses,Michael P. Weiner +8 more
TL;DR: A rapid, high throughput readout for single-nucleotide polymorphism (SNP) analysis was developed employing single base chain extension and cytometric analysis of an array of fluorescent microspheres coupled with uniquely identifying sequences, termed complementary ZipCodes (cZipCodes), which allowed for multiplexing possibilities.
Journal ArticleDOI
Flow cytometric platform for high-throughput single nucleotide polymorphism analysis.
J D Taylor,D Briley,Q Nguyen,K Long,Marie A. Iannone,May-Sung Li,F Ye,A Afshari,Eric H. Lai,M Wagner,Jingwen Chen,Michael P. Weiner +11 more
TL;DR: A new assay based on allele-specific primer extension (ASPE) was validated on a set of 15 multiplexed SNPs for 96 patients, which offers both the advantage of streamlining the SNP analysis protocol and the ability to perform multiplex SNP analysis on any mixture of allelic variants.
Journal ArticleDOI
Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist
Barry G. Shearer,David J. Steger,James M. Way,Thomas B. Stanley,David C. Lobe,Didier Grillot,Marie A. Iannone,Mitchell A. Lazar,Timothy M. Willson,Andrew N. Billin +9 more
TL;DR: The first report of a PPARbeta/delta small molecule antagonist ligand is described, which will be a useful tool for elucidating the biological roles of PPAR beta/ delta.