Kathryn L. Kellar

TL;DR: It is shown that zymosan, a stimulus for TLR2 and dectin-1, regulates cytokine secretion in DCs and macrophages to induce immunological tolerance and suggest several targets for pharmacological modulation of immune responses in various clinical settings.

TL;DR: The speed, sensitivity, and accuracy of flow cytometric detection of multiple binding events measured in the same small volume have the potential to replace many clinical diagnostic and research methods and deliver data on hundreds of analytes simultaneously.

TL;DR: Fluorescent bead-based immunoassays can be used to quantitate multiple cytokine levels in human sera and contribute to an understanding of the role of cytokines in disease processes.

TL;DR: This paper presents a method of multiplexed analysis that combines simultaneous quantitation of multiple cytokines in a small sample volume and shows that this method has become rapid, inexpensive, reliable and informative.

TL;DR: A workshop held by the Centers for Disease Control and Prevention that discussed issues surrounding multiplexed assays and the Luminex 100 xMAP instrument is summarized.