M
Marie-Laure Teyssot
Researcher at Centre national de la recherche scientifique
Publications - 4
Citations - 548
Marie-Laure Teyssot is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Cell cycle checkpoint & Adduct. The author has an hindex of 4, co-authored 4 publications receiving 507 citations. Previous affiliations of Marie-Laure Teyssot include Blaise Pascal University.
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Metal-NHC complexes: a survey of anti-cancer properties
Marie-Laure Teyssot,Marie-Laure Teyssot,Anne-Sophie Jarrousse,Anne-Sophie Jarrousse,Michèle Manin,Michèle Manin,Aurélien Chevry,Aurélien Chevry,Stéphane P. Roche,Stéphane P. Roche,Frédéric Norre,Frédéric Norre,Claude Beaudoin,Claude Beaudoin,Laurent Morel,Laurent Morel,Damien Boyer,Damien Boyer,Rachid Mahiou,Rachid Mahiou,Arnaud Gautier,Arnaud Gautier +21 more
TL;DR: Most of the metal-N-Heterocyclic Carbenes considered display higher cytotoxicities than the reference metallo-drug cisplatin, and their mechanisms of action at the cellular level are discussed, showing that the nature of themetal is of great importance.
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Anticancer Activity of Silver–N‐Heterocyclic Carbene Complexes: Caspase‐Independent Induction of Apoptosis via Mitochondrial Apoptosis‐Inducing Factor (AIF)
Laure Eloy,Anne-Sophie Jarrousse,Marie-Laure Teyssot,Arnaud Gautier,Laurent Morel,Claude Jolivalt,Thierry Cresteil,Sylvain Roland +7 more
TL;DR: Results demonstrate that silver–NHCs induce cancer cell death independent of the caspase cascade via the mitochondrial AIF pathway, and use of a fluorescent complex showed thatsilver–N HCs target mitochondria.
Journal ArticleDOI
Toxicity of Copper(I)-NHC Complexes Against Human Tumor Cells: Induction of Cell Cycle Arrest, Apoptosis, and DNA Cleavage
Marie-Laure Teyssot,Anne-Sophie Jarrousse,Aurélien Chevry,Angélique de Haze,Claude Beaudoin,Michèle Manin,Steven P. Nolan,Silvia Díez-González,Laurent Morel,Arnaud Gautier +9 more
TL;DR: Results of the biological evaluation of the anticancer properties of [(SIMes)CuCl] 5 evidenced that employing NHC to deliver active copper(I) species in cellulo is a valuable strategy in anticancer research.
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Bis-Heteronucleophilic Michael Addition to Divinyl Sulfone: A New Efficient Access to Macrocycles
TL;DR: In this article, the structures of some new macrocyclic sulfones are established by X-ray crystallographic analysis and NMR spectroscopy, and the subsequent cleavage of benzyl or tosyl groups yields the unprotected macro cyclic sulfone.