M
Marie S. Tuttle
Researcher at University of Utah
Publications - 3
Citations - 4155
Marie S. Tuttle is an academic researcher from University of Utah. The author has contributed to research in topics: Protein subunit & Sequence motif. The author has an hindex of 3, co-authored 3 publications receiving 3774 citations.
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Journal ArticleDOI
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
Elizabeta Nemeth,Marie S. Tuttle,Julie Powelson,Michael B. Vaughn,Adriana Donovan,Diane M. Ward,Tomas Ganz,Jerry Kaplan +7 more
TL;DR: It is reported that hepcidin bound to ferroportin in tissue culture cells, leading to decreased export of cellular iron and the posttranslational regulation of ferroports by hePCidin may complete a homeostatic loop.
Journal ArticleDOI
hVPS41 Is Expressed in Multiple Isoforms and Can Associate with Vesicles through a RING-H2 Finger Motif
Diane M. Ward,Derek C. Radisky,Matthew A. Scullion,Marie S. Tuttle,Michael B. Vaughn,Jerry Kaplan +5 more
TL;DR: Evidence is provided that hVps41, the human homologue of Vps41p, is expressed in two isoforms that differ in that one contains a C-terminal RING-H2 sequence motif, which suggests that this Ringer H2 domain is responsible for membrane association.
Journal ArticleDOI
A dominant allele of PDR1 alters transition metal resistance in yeast
TL;DR: Results suggest that expression of PDR1-regulated genes affects both efflux and storage of transition metals, as well as increased resistance to drugs such as cycloheximide and oligomycin.