M
Marie-Sophie Martina
Researcher at Capsugel
Publications - 8
Citations - 732
Marie-Sophie Martina is an academic researcher from Capsugel. The author has contributed to research in topics: Liposome & Preclinical imaging. The author has an hindex of 5, co-authored 8 publications receiving 700 citations. Previous affiliations of Marie-Sophie Martina include University of Paris-Sud.
Papers
More filters
Journal ArticleDOI
Generation of Superparamagnetic Liposomes Revealed as Highly Efficient MRI Contrast Agents for in Vivo Imaging
Marie-Sophie Martina,Jean-Paul Fortin,Christine Ménager,Olivier Clément,Gillian Barratt,Cécile Grabielle-Madelmont,Florence Gazeau,Valérie Cabuil,Sylviane Lesieur +8 more
TL;DR: In biological media, MFLs were highly stable and avoided ferrofluid flocculation while being nontoxic toward the J774 macrophage cell line, and steric stabilization ensured by PEG-surface-grafting significantly reduced liposome association with the macrophages.
Journal ArticleDOI
Magnetic Targeting of Magnetoliposomes to Solid Tumors with MR Imaging Monitoring in Mice: Feasibility
Jean-Paul Fortin-Ripoche,Marie-Sophie Martina,Florence Gazeau,Christine Ménager,Claire Wilhelm,Jean-Claude Bacri,Sylviane Lesieur,Olivier Clément +7 more
TL;DR: Magnetic targeting of sterically stabilized magnetoliposomes after they are intravenously injected is feasible in vivo.
Journal ArticleDOI
Sterically stabilized superparamagnetic liposomes for MR imaging and cancer therapy: pharmacokinetics and biodistribution.
TL;DR: Despite partial uptake in the earlier times after administration, MFLs exhibited long circulation behaviour over a 24-h period that, coupled to magnetic targeting, encourages further use in drug delivery.
Journal ArticleDOI
Magnetic Targeting of Nanometric Magnetic Fluid–loaded Liposomes to Specific Brain Intravascular Areas: A Dynamic Imaging Study in Mice
Charlotte Rivière,Marie-Sophie Martina,Yutaka Tomita,Claire Wilhelm,Alexy Tran Dinh,Christine Ménager,Elisabeth Pinard,Sylviane Lesieur,Florence Gazeau,Jacques Seylaz +9 more
TL;DR: Real-time in vivo imaging of rhodamine-labeled MFLs in the mouse brain cortex revealed that these nanosystems can be magnetically targeted, through microvessels, to selected brain areas.
Journal ArticleDOI
Magnetic targeting of rhodamine-labeled superparamagnetic liposomes to solid tumors: in vivo tracking by fibered confocal fluorescence microscopy.
Marie-Sophie Martina,Jean-Paul Fortin,Laure Fournier,Christine Ménager,Florence Gazeau,Olivier Clément,Sylviane Lesieur +6 more
TL;DR: Polyethylene glycol (PEG)ylated and rhodamine-labeled liposomes loaded with maghemite nanocrystals provide a novel nanoscaled hybrid system for magnetic targeting to solid tumors in possible combination with double in vivo imaging by fluorescence microscopy and magnetic resonance imaging (MRI).