Marie-Theres Gansauge

TL;DR: The results prove that authentic ancient DNA can be preserved for hundreds of thousand years outside of permafrost and enable the retrieval of phylogenetically informative sequences from samples in which virtually all DNA is diminished to fragments shorter than 50 bp.

TL;DR: This protocol describes a method for converting short single-Stranded and double-stranded DNA into libraries compatible with high-throughput sequencing using Illumina technology, and it is estimated that intact DNA strands are recovered in the library with ∼50% efficiency.

TL;DR: Both pretreatment methods described here greatly reduce the cost of genome sequencing from ancient material due to efficient depletion of microbial DNA, and it is found that the removal of human DNA contamination remains a challenging problem.

TL;DR: It is found that single-stranded library preparation increases library yields from tissues stored in formalin for many years by several orders of magnitude and is less costly and better compatible with automation.

TL;DR: The number of Denisovan individuals known to three is extended to three, with the nuclear DNA sequence diversity among the three Denisovans is comparable to that among six Neandertals, but lower than that among present-day humans.