M
Marilyn Carrier
Researcher at McGill University
Publications - 6
Citations - 626
Marilyn Carrier is an academic researcher from McGill University. The author has contributed to research in topics: Retinoic acid receptor alpha & Retinoic acid receptor. The author has an hindex of 5, co-authored 5 publications receiving 560 citations.
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Journal ArticleDOI
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.
Regina Cencic,Marilyn Carrier,Gabriela Galicia-Vázquez,Marie Eve Bordeleau,Rami Sukarieh,Annie Bourdeau,Brigitte Brem,Jose G. Teodoro,Harald Greger,Michel L. Tremblay,John A. Porco,Jerry Pelletier +11 more
TL;DR: In this article, the authors presented the results of the Canadian Institutes of Health Research (CIHR) Training Grant and the US Lymphoma Foundation Training Grant (USLGF).
Journal ArticleDOI
Vitamin D Induces Interleukin-1β Expression: Paracrine Macrophage Epithelial Signaling Controls M. tuberculosis Infection
Mark Verway,Manuella Bouttier,Tian-Tian Wang,Marilyn Carrier,Mario R. Calderon,Beum-Soo An,Emmanuelle Devemy,Fiona McIntosh,Maziar Divangahi,Marcel A. Behr,John H. White +10 more
TL;DR: Evidence is provided that the anti-microbial actions of vitamin D extend beyond the macrophage by modulating paracrine signaling, reinforcing its role in innate immune regulation in humans.
Journal ArticleDOI
Altering Chemosensitivity by Modulating Translation Elongation
Francis Robert,Marilyn Carrier,Svea Rawe,Samuel Huan-Tang Chen,Scott W. Lowe,Jerry Pelletier +5 more
TL;DR: The results indicate that depleting short-lived pro-survival factors by inhibiting their synthesis could achieve a therapeutic response in tumors harboring PTEN/AKT/mTOR pathway mutations.
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Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells
TL;DR: This work investigates the sensitivity of acute myelogenous leukemia (AML) cell lines to protein synthesis inhibition in combination with the standard cytotoxic agents daunorubicin, etoposide, and cytarabine and shows synergy with standard-of-care agents in AML cell lines.
Journal ArticleDOI
Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA.
Alexander S. Wahba,Fereshteh Azizi,Glen F. Deleavey,Claire M. Brown,Francis Robert,Marilyn Carrier,Anna Kalota,Alan M. Gewirtz,Jerry Pelletier,Robert H. E. Hudson,Masad J. Damha +10 more
TL;DR: These findings demonstrate that PhpC-modified siRNAs retain the properties of natural si RNAs while allowing for fluorescence-based detection and monitoring, providing an ideal system for probing siRNA uptake and trafficking.