M
Mário Ramirez
Researcher at Instituto de Medicina Molecular
Publications - 143
Citations - 6591
Mário Ramirez is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 40, co-authored 137 publications receiving 5723 citations. Previous affiliations of Mário Ramirez include Universidade Nova de Lisboa & University of Lisbon.
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Increasing macrolide resistance among Streptococcus agalactiae causing invasive disease in non-pregnant adults was driven by a single capsular-transformed lineage, Portugal, 2009 to 2015.
Elísia Lopes,Tânia Fernandes,Miguel P. Machado,João A. Carriço,José Melo-Cristino,Mário Ramirez,E. R. Martins +6 more
TL;DR: Expansion of the new serotype Ib/CC1 lineage resulted in increased macrolide resistance in GBS, causing invasive disease among adults in Portugal and may predict more widespread increase in resistance.
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The autolysin LytA contributes to efficient bacteriophage progeny release in Streptococcus pneumoniae.
TL;DR: It is demonstrated that S. pneumoniae phages use the ubiquitous host autolysin to accomplish an optimal phage exiting strategy and that activation of bacterial LytA, together with the phage lysin, leads to greater phage progeny release.
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Superantigen gene complement of Streptococcus pyogenes—relationship with other typing methods and short-term stability
TL;DR: The results suggest that the SAg profile diversifies faster than other properties commonly used for molecular typing, such as emm type and multilocus sequence typing (MLST) sequence types (STs), and can be a useful complement in GAS molecular epidemiology.
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Pherotypes are driving genetic differentiation within Streptococcus pneumoniae
TL;DR: Standard population genetic analysis and multilocus infinite allele model simulations support the hypothesis that two genetically differentiated populations are defined by the major pherotypes, and it is shown that pherotype is a clonal property of pneumococci.
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Changes in Streptococcus pyogenes causing invasive disease in Portugal: evidence for superantigen gene loss and acquisition.
TL;DR: An ongoing genomic diversification of GAS invasive isolates in Portugal may contribute to the persistence of clones with improved fitness or virulence, as indicated by both PFGE profiling and emm typing.