M
Mário Ramirez
Researcher at Instituto de Medicina Molecular
Publications - 143
Citations - 6591
Mário Ramirez is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Serotype & Multilocus sequence typing. The author has an hindex of 40, co-authored 137 publications receiving 5723 citations. Previous affiliations of Mário Ramirez include Universidade Nova de Lisboa & University of Lisbon.
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Journal ArticleDOI
Streptococcus pyogenes Causing Skin and Soft Tissue Infections Are Enriched in the Recently Emerged emm89 Clade 3 and Are Not Associated With Abrogation of CovRS.
TL;DR: The results indicate that the isolates responsible for SSTI are genetically distinct from those recovered from normally sterile sites, supporting a role for mutations impairing CovRS activity specifically in invasive infection and suggesting that this role relies on a differential regulation of other virulence factors besides SpeB.
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Conjugate vaccine serotypes persist as major causes of non-invasive pneumococcal pneumonia in Portugal despite declines in serotypes 3 and 19A (2012-2015).
TL;DR: The introduction of PCV13 in the national immunization program for children from 2015 onwards may lead to reductions in the proportion of NIPP due to vaccine serotypes but continued NIPP surveillance is essential due to a different serotype distribution from invasive disease.
Journal ArticleDOI
Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease
TL;DR: The overall proportion of piliated isolates declined in the period following PCV7 but quickly recovered to pre-PCV7 levels (50%) and the proportion of isolates carrying both pilus islands remained stable and low.
Journal ArticleDOI
Identification of immunoreactive extracellular proteins of Streptococcus agalactiae in bovine mastitis.
Gabriela Trigo,Paula Ferreira,Niza RibeiroN. Ribeiro,Márcia Dinis,Elva Bonifácio Andrade,José Melo-Cristino,Mário Ramirez,Delfina Tavares +7 more
TL;DR: Group B protective surface protein and 5'-nucleotidase family protein were 2 major immunoreactive proteins that were detected only in the whey of infected cows, suggesting that these proteins may be important in the pathogenesis of S. agalactiae-induced mastitis.
Posted ContentDOI
Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers
Patrícia Figueiredo-Campos,Birte Blankenhaus,Catarina Mota,Andreia Gomes,Marta Serrano,Silvia Ariotti,Catarina Costa,Helena Nunes-Cabaço,António M. Mendes,Pedro Gaspar,Pereira-Santos Cm,Filipe B. Rodrigues,Jorge Condeço,Escoval Am,Maria José Santos,Mário Ramirez,José Melo-Cristino,Simas Pj,Simas Pj,Eugenia Vasconcelos,A. Afonso,Marc Veldhoen +21 more
TL;DR: This work quantified immunoglobulin M, IgG and IgA antibodies recognizing the SARS-CoV-2 receptor-binding domain (RBD) or the Spike (S) protein over a period of five months following COVID-19 disease onset or in previously Sars-Cov-2 PCR-positive volunteers, and highlighted a continued level of circulating neutralising antibodies in most people with confirmed SARS, at least up to five months after infection.