M
Mario Thevis
Researcher at German Sport University Cologne
Publications - 512
Citations - 13310
Mario Thevis is an academic researcher from German Sport University Cologne. The author has contributed to research in topics: Mass spectrometry & Metabolite. The author has an hindex of 53, co-authored 476 publications receiving 11753 citations. Previous affiliations of Mario Thevis include Saarland University & University of California, Los Angeles.
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Nutritional supplements cross-contaminated and faked with doping substances
TL;DR: Since 2002 new 'designer' steroids such as prostanozol, methasterone, androstatrienedione etc have been offered on the nutritional supplement market and also cross-contamination with these steroids are expected.
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Factors influencing the steroid profile in doping control analysis
TL;DR: Pharmaceutical (application of endogenous steroids and various pharmaceutical preparations), technical (hydrolysis, derivatization, matrix), and biological (bacterial activities, enzyme side activities) issues are reviewed.
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Δ6‐Desaturase (FADS2) deficiency unveils the role of ω3‐ and ω6‐polyunsaturated fatty acids
Wilhelm Stoffel,Barbara Holz,Britta Jenke,Erika Binczek,Robert Heinz Günter,Christine Kiss,Iakowos Karakesisoglou,Mario Thevis,Artur-Aron Weber,Stephan Arnhold,Klaus Addicks +10 more
TL;DR: It is shown that deletion of Δ6‐fatty acid desaturase (FADS2) gene expression in the mouse abolishes the initial step in the enzymatic cascade of PUFA synthesis, and is anticipated that FADS2 will become a major focus in membrane, haemostasis, inflammation and atherosclerosis research.
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Mass spectrometry in sports drug testing: Structure characterization and analytical assays
Mario Thevis,Wilhelm Schänzer +1 more
TL;DR: The versatility of modern mass spectrometers enable specific as well as comprehensive measurements allowing sports drug testing laboratories to determine the misuse of therapeutics such as anabolic-androgenic steroids, stimulants, masking agents or so-called designer drugs in athletes' blood or urine specimens, and a selection of recent developments is summarized in this review.
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Determination of 13C/12C ratios of endogenous urinary steroids: method validation, reference population and application to doping control purposes.
Thomas Piper,Ute Mareck,Hans Geyer,Ulrich Flenker,Mario Thevis,Petra Platen,Wilhelm Schänzer +6 more
TL;DR: The application of a comprehensive gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS)-based method for stable carbon isotopes of endogenous urinary steroids is presented, which covers repeatability and reproducibility.