M
Marjolein A Heuvelmans
Researcher at University Medical Center Groningen
Publications - 90
Citations - 4242
Marjolein A Heuvelmans is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Lung cancer screening & Lung cancer. The author has an hindex of 21, co-authored 69 publications receiving 2473 citations. Previous affiliations of Marjolein A Heuvelmans include Medisch Spectrum Twente & Erasmus University Rotterdam.
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Journal ArticleDOI
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial
Harry J. de Koning,Carlijn M. van der Aalst,Pim A. de Jong,Ernst Th. Scholten,Kristiaan Nackaerts,Marjolein A Heuvelmans,Jan-Willem J. Lammers,Carla Weenink,Uraujh Yousaf-Khan,Nanda Horeweg,Susan van 't Westeinde,Mathias Prokop,Willem P.Th.M. Mali,Firdaus A. A. Mohamed Hoesein,Peter M. A. van Ooijen,Joachim G.J.V. Aerts,Michael A. den Bakker,Erik Thunnissen,Johny Verschakelen,Rozemarijn Vliegenthart,Joan Walter,Kevin ten Haaf,Harry J.M. Groen,Matthijs Oudkerk +23 more
TL;DR: In this trial involving high-risk persons, lung-cancer mortality was significantly lower among those who underwent volume CT screening than among thoseWho underwent no screening.
Journal ArticleDOI
European position statement on lung cancer screening
Matthijs Oudkerk,Anand Devaraj,Rozemarijn Vliegenthart,Thomas Henzler,Helmut Prosch,Claus P. Heussel,Claus P. Heussel,Gorka Bastarrika,Nicola Sverzellati,Mario Mascalchi,Stefan Delorme,David R Baldwin,Matthew E.J. Callister,Nikolaus Becker,Marjolein A Heuvelmans,Witold Rzyman,Maurizio Infante,Ugo Pastorino,Jesper Holst Pedersen,Eugenio Paci,Stephen W. Duffy,Harry J. de Koning,John K. Field +22 more
TL;DR: A risk stratification approach should be used for future lung cancer low-dose CT programmes and patients should be provided with information on the benefits and harms of screening to ensure that patients receive the most appropriate treatment.
Journal ArticleDOI
Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening
Nanda Horeweg,Joost van Rosmalen,Marjolein A Heuvelmans,Carlijn M. van der Aalst,Rozemarijn Vliegenthart,Ernst T. Scholten,Kevin ten Haaf,Kristiaan Nackaerts,Jan-Willem J. Lammers,Carla Weenink,Harry J.M. Groen,Peter M. A. van Ooijen,Pim A. de Jong,Geertruida H. de Bock,Willem P.Th.M. Mali,Harry J. de Koning,Matthijs Oudkerk +16 more
TL;DR: This prespecified analysis quantifies how nodule diameter, volume, and volume doubling time affect the probability of developing lung cancer within 2 years of a CT scan, and proposes and evaluates thresholds for management protocols.
Journal ArticleDOI
Detection of lung cancer through low-dose CT screening (NELSON): A prespecified analysis of screening test performance and interval cancers
Nanda Horeweg,Ernst T. Scholten,Pim A. de Jong,Carlijn M. van der Aalst,Carla Weenink,Jan-Willem J. Lammers,Kristiaan Nackaerts,Rozemarijn Vliegenthart,Kevin ten Haaf,Uraujh Yousaf-Khan,Marjolein A Heuvelmans,Erik Thunnissen,Matthijs Oudkerk,Willem P.Th.M. Mali,Harry J. de Koning +14 more
TL;DR: Lung cancer screening in the NELSON trial yielded high specificity and sensitivity, with only a small number of interval cancers, which could be used to improve screening algorithms.
Journal ArticleDOI
Final screening round of the NELSON lung cancer screening trial : the effect of a 2.5-year screening interval
Uraujh Yousaf-Khan,Carlijn M. van der Aalst,Pim A. de Jong,Marjolein A Heuvelmans,Ernst T. Scholten,Jan-Willem J. Lammers,Peter M. A. van Ooijen,Kristiaan Nackaerts,Carla Weenink,Harry J.M. Groen,Rozemarijn Vliegenthart,Kevin ten Haaf,Matthijs Oudkerk,Harry J. de Koning +13 more
TL;DR: Results provide results of the fourth screening round after a 2.5-year interval in the Dutch-Belgian Lung Cancer Screening trial (NELSON), which showed the effect of screening was reduced: the interval cancer rate was higher compared with the 1-year and 2-year intervals, and proportion of advanced disease stage in the final round was higher than with the previous rounds.