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Mark A. Sperling

Researcher at Icahn School of Medicine at Mount Sinai

Publications -  170
Citations -  7697

Mark A. Sperling is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Insulin & Glucagon. The author has an hindex of 40, co-authored 167 publications receiving 7032 citations. Previous affiliations of Mark A. Sperling include Beaumont Hospital & University of Cincinnati Academic Health Center.

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ISPAD Clinical Practice Consensus Guidelines 2018: Diabetic ketoacidosis and the hyperglycemic hyperosmolar state.

TL;DR: Recommendations concerning fluid management have been modified to reflect recent findings from a randomized controlled clinical trial showing no difference in cerebral injury in patients rehydrated at different rates with either 0.45% or 0.9% saline.
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Insulin resistance in short children with intrauterine growth retardation.

TL;DR: Short prepubertal IUGR children have a specific impairment in insulin sensitivity compared to their normal birth weight peers, a potential marker for the early identification and intervention in the development of late adult-onset noninsulin-dependent diabetes mellitus.
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Measurement of “True” Glucose Production Rates in Infancy and Childhood with 6,6-Dideuteroglucose

TL;DR: The first measurements of “new” glucose production in childhood, measured in 54 infants and children for the first time, suggest that brain size may be a principal determinant of those factors that regulate hepatic glucose output throughout life.
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Diabetic Ketoacidosis in Infants, Children, and Adolescents: A consensus statement from the American Diabetes Association

TL;DR: Infants and toddlers in DKA may be misdiagnosed as having pneumonia, reactive airways disease (asthma), or bronchiolitis and therefore treated with glucocorticoids and/or sympathomimetic agents that only compound and exacerbate the metabolic derangements.