M
Mark G. Coulthard
Researcher at University of Queensland
Publications - 53
Citations - 1420
Mark G. Coulthard is an academic researcher from University of Queensland. The author has contributed to research in topics: Erythropoietin-producing hepatocellular (Eph) receptor & Ephrin. The author has an hindex of 20, co-authored 51 publications receiving 1271 citations. Previous affiliations of Mark G. Coulthard include QIMR Berghofer Medical Research Institute & Royal Children's Hospital.
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Journal ArticleDOI
Eph/Ephrin signaling in injury and inflammation.
Mark G. Coulthard,Michael M. Morgan,Trent M. Woodruff,Thiruma V. Arumugam,Stephen M. Taylor,Todd C. Carpenter,Martin Lackmann,Andrew W. Boyd,Andrew W. Boyd,Andrew W. Boyd +9 more
TL;DR: Although there remains much to learn about Eph/ephrin signaling in human disease, and specifically in injury and inflammation, this area of research raises the exciting prospect that novel therapies will be developed that precisely target these pathways.
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Increased DNA methylation at the AXIN1 gene in a monozygotic twin from a pair discordant for a caudal duplication anomaly.
Nathan A. Oates,Nathan A. Oates,J. van Vliet,David L. Duffy,Hester Y. Kroes,Nicholas G. Martin,Dorret I. Boomsma,Megan Campbell,Mark G. Coulthard,Mark G. Coulthard,Emma Whitelaw,Emma Whitelaw,Suyinn Chong +12 more
TL;DR: It is confirmed that this CpG island does function as a promoter in vitro and that its activity is inversely proportional to the extent of methylation, raising the possibility that hypermethylation of the AXIN1 promoter, by mechanisms as yet undetermined, is associated with the malformation.
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Isotonic versus hypotonic solutions for maintenance intravenous fluid administration in children.
Sarah McNab,Robert S. Ware,Kristen A Neville,Karen Choong,Mark G. Coulthard,Trevor Duke,Andrew Davidson,Tavey Dorofaeff +7 more
TL;DR: Isotonic intravenous maintenance fluids with sodium concentrations similar to that of plasma reduce the risk of hyponatraemia when compared with hypotonic intravenously fluids.
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Systematic review of the diagnostic accuracy of C-reactive protein to detect bacterial infection in nonhospitalized infants and children with fever.
TL;DR: CRP provides moderate and independent information for both ruling in and ruling out serious bacterial infection in children with fever at first presentation, and poor sensitivity means that CRP cannot be used to exclude all bacterial infection.
Journal ArticleDOI
The role of the Eph-ephrin signalling system in the regulation of developmental patterning.
Mark G. Coulthard,Shannon Duffy,Michelle Down,Betty Evans,Maryanne Power,Fiona M. Smith,Con Stylianou,Sabine Kleikamp,Andrew C. Oates,Martin Lackmann,Gordon F. Burns,Andrew W. Boyd +11 more
TL;DR: This review focuses on two vertebrate models, the zebrafish and mouse, in which experimental perturbation of Eph and/or ephrin expression in vivo have provided important insights into the role and functioning of the Eph/ephrin system.